PDBe 6dfk

X-ray diffraction
3.1Å resolution

Crystal structure of the 11S subunit of the Plasmodium falciparum proteasome, PA28

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo heptamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
PA28_beta domain-containing protein Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N
Length: 280 amino acids
Theoretical weight: 33.24 KDa
Source organism: Plasmodium falciparum 3D7
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8I374 (Residues: 1-279; Coverage: 100%)
Gene name: PF3D7_0907700
Sequence domains: Proteasome activator pa28 beta subunit

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: P3121
Unit cell:
a: 166.485Å b: 166.485Å c: 399.162Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.183 0.182 0.225
Expression system: Escherichia coli BL21(DE3)