EC 1.14.14.73: Albendazole monooxygenase (sufoxide-forming)
Reaction catalysed:
Albendazole + [reduced NADPH--hemoprotein reductase] + O(2) = albendazole S-oxide + [oxidized NADPH--hemoprotein reductase] + H(2)O
Systematic name:
Albendazole,[reduced NADPH--hemoprotein reductase]:oxygen oxidoreductase (sufoxide-forming)
Alternative Name(s):
- Albendazole hydroxylase
- Albendazole sulfoxidase
- CYP1A2
- CYP2J2
- CYP3A4
EC 1.14.14.56: 1,8-cineole 2-exo-monooxygenase
Reaction catalysed:
1,8-cineole + [reduced NADPH--hemoprotein reductase] + O(2) = 2-exo-hydroxy-1,8-cineole + [oxidized NADPH--hemoprotein reductase] + H(2)O
Systematic name:
1,8-cineole,[reduced NADPH--hemoprotein reductase]:oxygen oxidoreductase (2-exo-hydroxylating)
Alternative Name(s):
- CYP3A4
EC 1.14.14.55: Quinine 3-monooxygenase
Reaction catalysed:
Quinine + [reduced NADPH--hemoprotein reductase] + O(2) = 3-hydroxyquinine + [oxidized NADPH--hemoprotein reductase] + H(2)O
Systematic name:
Quinine,[reduced NADPH--hemoprotein reductase]:oxygen oxidoreductase
Alternative Name(s):
- CYP3A4
- Nifedipine oxidase
- Quinine 3-hydroxylase
EC 1.14.14.1: Unspecific monooxygenase
Reaction catalysed:
RH + [reduced NADPH--hemoprotein reductase] + O(2) = ROH + [oxidized NADPH--hemoprotein reductase] + H(2)O
Systematic name:
Substrate,reduced-flavoprotein:oxygen oxidoreductase (RH-hydroxylating or -epoxidizing)
Alternative Name(s):
- Aryl hydrocarbon hydroxylase
- Aryl-4-monooxygenase
- Cytochrome P450
- Flavoprotein monooxygenase
- Flavoprotein-linked monooxygenase
- Microsomal P-450
- Microsomal P450
- Microsomal monooxygenase
- Xenobiotic monooxygenase
GO terms
Biochemical function:
- 1,8-cineole 2-exo-monooxygenase activity
- estrogen 2-hydroxylase activity
- estrogen 16-alpha-hydroxylase activity
- vitamin D 24-hydroxylase activity
- aromatase activity
- anandamide 14,15 epoxidase activity
- anandamide 11,12 epoxidase activity
- anandamide 8,9 epoxidase activity
- 1-alpha,25-dihydroxyvitamin D3 23-hydroxylase activity
- testosterone 6-beta-hydroxylase activity
- quinine 3-monooxygenase activity
- metal ion binding
- caffeine oxidase activity
- vitamin D3 25-hydroxylase activity
- heme binding
- enzyme binding
- oxygen binding
- oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
- oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
- oxidoreductase activity
- retinoic acid 4-hydroxylase activity
- steroid hydroxylase activity
- protein binding
- iron ion binding
- steroid binding
- monooxygenase activity
Biological process:
- oxidative demethylation
- heterocycle metabolic process
- aflatoxin metabolic process
- long-chain fatty acid biosynthetic process
- retinoic acid metabolic process
- retinol metabolic process
- vitamin D catabolic process
- vitamin D metabolic process
- xenobiotic catabolic process
- calcitriol biosynthetic process from calciol
- monoterpenoid metabolic process
- alkaloid catabolic process
- estrogen metabolic process
- androgen metabolic process
- cholesterol metabolic process
- steroid metabolic process
- xenobiotic metabolic process
- steroid catabolic process
- steroid biosynthetic process
- fatty acid metabolic process
- lipid metabolic process
- lipid hydroxylation
Protein family (Pfam)
InterPro annotations
CATH domain