6d97

X-ray diffraction
2.2Å resolution

Structure of aldehyde dehydrogenase 12 (ALDH12) from Zea mays

Released:

Function and Biology Details

Reaction catalysed:
L-glutamate 5-semialdehyde + NAD(+) + H(2)O = L-glutamate + NADH
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
homo tetramer
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Aldedh domain-containing protein Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 547 amino acids
Theoretical weight: 60.47 KDa
Source organism: Zea mays
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A2H4PMI3 (Residues: 17-549; Coverage: 97%)
Gene name: ALDH12
Sequence domains: Aldehyde dehydrogenase family

Ligands and Environments


Cofactor: Ligand NAD 4 x NAD
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 4.2.2
Spacegroup: C2
Unit cell:
a: 160.642Å b: 123.737Å c: 103.707Å
α: 90° β: 105.62° γ: 90°
R-values:
R R work R free
0.167 0.165 0.21
Expression system: Escherichia coli