› 6d57

X-ray diffraction
1.81Å resolution

Campylobacter jejuni ferric uptake regulator S1 metalated

Released:
DOI: 10.2210/pdb6d57/pdb
PDB entry 6d57 coloured by chain, front view.
PDB entry 6d57 coloured by chain, side view.
PDB entry 6d57 coloured by chain, top view.
Source organism: Campylobacter jejuni
Primary publication:
Functional insights into the interplay between DNA interaction and metal coordination in ferric uptake regulators.
Sarvan S, Charih F, Askoura M, Butcher J, Brunzelle JS, Stintzi A, Couture JF
Sci Rep 8 7140 (2018)
PMID: 29739988

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-103440 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ferric uptake regulation protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 161 amino acids
Theoretical weight: 18.41 KDa
Source organism: Campylobacter jejuni
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A1E7PHN7 (Residues: 1-157; Coverage: 100%)
Gene names: B7A03_01770, BFD99_04385, C1418_04340, C3H42_06740, C3H48_04340, C3H57_01855, C3H76_03520, C3I35_03570, DDV78_03710, DVI03_04920, E7N58_03050, E7N58_10245, E8P16_03970, E8P16_10730, F8Y55_03215, FBF07_00995, GFF90_05790, GNO00_03775, NCTC13105_01126, QQI97_001071, fur
Sequence domains: Ferric uptake regulator family
Structure domains:

Ligands and Environments

3 bound ligands:
Ligand GOL 3 x GOL
Ligand FMT 8 x FMT
Ligand ZN 2 x ZN
1 modified residue:
Ligand OHI 2 x OHI

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P212121
Unit cell:
a: 35.742Å b: 84.363Å c: 123.626Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.186 0.184 0.229
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Variation on a theme: investigating the structural repertoires used by ferric uptake regulators to control gene expression.
Sarvan et al. (2018)
2 more

2 mentions without citation

Functional insights into the interplay between DNA interaction and metal coordination in ferric uptake regulators.
Sarvan et al. (2018)
1 more