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Crystal structure of PT1614 bound to HIF2a-B*:ARNT-B* complex

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

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GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF14598
Domain description: PAS domain
Occurring in:
  1. Endothelial PAS domain-containing protein 1
  2. Aryl hydrocarbon receptor nuclear translocator
The deposited structure of PDB entry 6d0b contains 1 copy of Pfam domain PF14598 (PAS domain) in Endothelial PAS domain-containing protein 1. Showing 1 copy in chain A.
The deposited structure of PDB entry 6d0b contains 1 copy of Pfam domain PF14598 (PAS domain) in Aryl hydrocarbon receptor nuclear translocator. Showing 1 copy in chain B.

InterPro InterPro annotations
IPR000014
Domain description: PAS domain
Occurring in:
  1. Endothelial PAS domain-containing protein 1
  2. Aryl hydrocarbon receptor nuclear translocator
IPR001610
Domain description: PAC motif
Occurring in:
  1. Endothelial PAS domain-containing protein 1
  2. Aryl hydrocarbon receptor nuclear translocator
IPR035965
Domain description: PAS domain superfamily
Occurring in:
  1. Endothelial PAS domain-containing protein 1
  2. Aryl hydrocarbon receptor nuclear translocator
IPR013655
Domain description: PAS fold-3
Occurring in:
  1. Endothelial PAS domain-containing protein 1

Structure domain

CATH CATH domain
3.30.450.20
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: Beta-Lactamase
Homology: PAS domain
Occurring in:
  1. Endothelial PAS domain-containing protein 1
  2. Aryl hydrocarbon receptor nuclear translocator
The deposited structure of PDB entry 6d0b contains 1 copy of CATH domain 3.30.450.20 (Beta-Lactamase) in Endothelial PAS domain-containing protein 1. Showing 1 copy in chain A.
The deposited structure of PDB entry 6d0b contains 1 copy of CATH domain 3.30.450.20 (Beta-Lactamase) in Aryl hydrocarbon receptor nuclear translocator. Showing 1 copy in chain B.

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