› 6cw1

X-ray diffraction
2.84Å resolution

Crystal structure of Neurexin-1 alpha ectodomain fragment, L2-L3

Released:
DOI: 10.2210/pdb6cw1/pdb
PDB entry 6cw1 coloured by chain, front view.
PDB entry 6cw1 coloured by chain, side view.
PDB entry 6cw1 coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
Structural Plasticity of Neurexin 1α: Implications for its Role as Synaptic Organizer.
Liu J, Misra A, Reddy MVVVS, White MA, Ren G, Rudenko G
J Mol Biol 430 4325-4343 (2018)
PMID: 30193986

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-173308 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neurexin-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 402 amino acids
Theoretical weight: 44.52 KDa
Source organism: Bos taurus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q28146 (Residues: 258-690; Coverage: 27%)
Gene name: NRXN1
Sequence domains: Laminin G domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-D
Spacegroup: P21
Unit cell:
a: 87.144Å b: 62.901Å c: 113.061Å
α: 90° β: 97.1° γ: 90°
R-values:
R R work R free
0.223 0.222 0.255
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 review citation

Neurexins - versatile molecular platforms in the synaptic cleft.
Rudenko G. (2019)
5 other articles

1 mention without citation

Structural Plasticity of Neurexin 1α: Implications for its Role as Synaptic Organizer.
Liu et al. (2018)