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HADDOCK structure of the Rous sarcoma virus matrix protein (M-domain) in complex with myo-inositol hexakisphosphate

Solution NMR
PDB entry 6cus coloured by chain, ensemble of 20 models, front view.
PDB entry 6cus coloured by chain, ensemble of 20 models, side view.
PDB entry 6cus coloured by chain, ensemble of 20 models, top view.
Source organism: Rous sarcoma virus - Prague C
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Integrase
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Multimeric state: monomeric
Accessible surface area: 5476.69 Å2
Buried surface area: 499.57 Å2
Dissociation area: 249.78 Å2
Dissociation energy (ΔGdiss): 0.86 kcal/mol
Dissociation entropy (TΔSdiss): 5.55 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-136816

Macromolecules

Matrix protein p19
Chain: A
Length: 87 amino acids
Theoretical weight: 9.21 KDa
Source organism: Rous sarcoma virus - Prague C
Expression system: Escherichia coli
UniProt:
  • Canonical: P03354 (Residues: 1-87; Coverage: 5%)
Gene name: gag-pol
Pfam: Retroviral M domain
InterPro:
Matrix protein p19 in PDB entry 6cus, assembly 1, front view.
Matrix protein p19 in PDB entry 6cus, assembly 1, side view.
Matrix protein p19 in PDB entry 6cus, assembly 1, top view.
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