PDBe 6cug

X-ray diffraction
2.4Å resolution

Crystal structure of BC8B TCR-CD1b-PC complex

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
T-cell surface glycoprotein CD1b Chain: A
Molecule details ›
Chain: A
Length: 300 amino acids
Theoretical weight: 33.53 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: NEW P29016 (Residues: 20-296; Coverage: 88%)
Gene name: CD1B
Sequence domains: Immunoglobulin C1-set domain
Beta-2-microglobulin Chain: B
Molecule details ›
Chain: B
Length: 99 amino acids
Theoretical weight: 11.75 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: NEW P61769 (Residues: 21-119; Coverage: 100%)
Gene names: B2M, CDABP0092, HDCMA22P
Sequence domains: Immunoglobulin C1-set domain
T-cell receptor alpha variable TRAV9-2 - BC8B TCR Chain: D
Molecule details ›
Chain: D
Length: 207 amino acids
Theoretical weight: 22.73 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
T-cell receptor beta variable TRBV6-2 - BC8B TCR Chain: E
Molecule details ›
Chain: E
Length: 245 amino acids
Theoretical weight: 27.6 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: P21
Unit cell:
a: 73.3Å b: 65.7Å c: 101.9Å
α: 90° β: 100.7° γ: 90°
R-values:
R R work R free
0.189 0.187 0.229
Expression systems:
  • Homo sapiens
  • Escherichia coli BL21(DE3)