› 6cu5

X-ray diffraction
2.7Å resolution

Crystal structure of a protein arginine N-methyltransferase from Naegleria fowleri bound to SAH

Released:
DOI: 10.2210/pdb6cu5/pdb
PDB entry 6cu5 coloured by chain, front view.
PDB entry 6cu5 coloured by chain, side view.
PDB entry 6cu5 coloured by chain, top view.
Source organism: Naegleria fowleri
Entry author: Seattle Structural Genomics Center for Infectious Disease (SSGCID)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-104732 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Methyltransferase domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 336 amino acids
Theoretical weight: 38.7 KDa
Source organism: Naegleria fowleri
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A384E135 (Residues: 1-328; Coverage: 100%)
Sequence domains: Methyltransferase domain
Structure domains: Hnrnp arginine n-methyltransferase1

Ligands and Environments

1 bound ligand:
Ligand SAH 2 x SAH
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-F
Spacegroup: P21
Unit cell:
a: 43.2Å b: 101.45Å c: 80.68Å
α: 90° β: 100.1° γ: 90°
R-values:
R R work R free
0.196 0.188 0.266
Expression system: Escherichia coli

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