Function and Biology Details
Reaction catalysed:
Strict requirement for an Asp residue at position P1 and has a preferred cleavage sequence of Asp-Glu-Val-Asp-|-
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero hexamer (preferred)
Assembly name:
Caspase-7 complex and peptide (preferred)
PDBe Complex ID:
PDB-CPX-157252 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Caspase-7 subunit p20
Molecule details ›
Chains: A, C
Length: 198 amino acids
Theoretical weight: 22.19 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Caspase domain
Structure domains: Rossmann fold
Length: 198 amino acids
Theoretical weight: 22.19 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P55210 (Residues: 1-198; Coverage: 65%)
Sequence domains: Caspase domain
Structure domains: Rossmann fold
Caspase-7 subunit p11
Molecule details ›
Chains: B, D
Length: 113 amino acids
Theoretical weight: 13.22 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Caspase domain
Structure domains: Caspase-like
Length: 113 amino acids
Theoretical weight: 13.22 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P55210 (Residues: 199-303; Coverage: 35%)
Sequence domains: Caspase domain
Structure domains: Caspase-like
