X-ray diffraction
1.8Å resolution

Candida albicans Hsp90 nucleotide binding domain in complex with SNX-2112


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Heat shock protein 90 homolog Chains: A, B
Molecule details ›
Chains: A, B
Length: 230 amino acids
Theoretical weight: 26.21 KDa
Source organism: Candida albicans SC5314
Expression system: Escherichia coli
  • Canonical: P46598 (Residues: 7-218; Coverage: 30%)
Gene names: CAALFM_C702030WA, CaJ7.0234, CaO19.13868, CaO19.6515, HSP90
Sequence domains: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
Structure domains: Histidine kinase-like ATPase, C-terminal domain

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-D
Spacegroup: P43
Unit cell:
a: 73.633Å b: 73.633Å c: 109.186Å
α: 90° β: 90° γ: 90°
R R work R free
0.173 0.173 0.22
Expression system: Escherichia coli