6cc0

X-ray diffraction
2.5Å resolution

Crystal structure of QscR bound to C12-homoserine lactone

Released:
Source organism: Pseudomonas aeruginosa
Entry authors: Churchill MEA, Wysoczynski-Horita CL

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
HTH luxR-type domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 237 amino acids
Theoretical weight: 27.29 KDa
Source organism: Pseudomonas aeruginosa
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9RMS5 (Residues: 1-237; Coverage: 100%)
Gene names: ALP65_03645, CAZ10_26210, DT376_23495, E4V10_12590, E5D53_22895, E5Z62_10125, E5Z63_30410, ECC04_019105, GUL26_19290, IPC111_15815, IPC112_31135, IPC113_31010, IPC114_30970, IPC115_30945, IPC116_18515, IPC117_19075, IPC118_07575, IPC119_12930, IPC120_03880, IPC121_16925, IPC122_15280, IPC123_04885, IPC124_20825, IPC125_14110, IPC126_21330, IPC127_18980, IPC128_16955, IPC129_08930, IPC1306_11955, IPC1307_10495, IPC1308_11820, IPC130_09660, IPC1310_03905, IPC1311_29530, IPC1312_07315, IPC1313_20420, IPC1314_07890, IPC1315_19200, IPC1316_10625, IPC1317_13620, IPC1318_14290, IPC1319_06485, IPC131_08885, IPC1320_02080, IPC1321_19600, IPC1322_24890, IPC1323_26100, IPC1324_25060, IPC1325_08775, IPC1326_10505, IPC1327_12165, IPC1329_08825, IPC132_09895, IPC1331_12220, IPC1332_15295, IPC1333_22580, IPC1335_17800, IPC1336_12130, IPC1337_19690, IPC1338_10850, IPC1339_17030, IPC133_14505, IPC1340_18280, IPC1341_14885, IPC1342_03050, IPC1343_09165, IPC1348_25325, IPC1349_30920, IPC134_13940, IPC135_16850, IPC137_15625, IPC139_06945, IPC140_11465, IPC141_06700, IPC142_00020, IPC143_10945, IPC144_16380, IPC145_24900, IPC146_19970, IPC1474_15700, IPC1476_27895, IPC1477_29635, IPC1478_26190, IPC1479_00020, IPC147_14485, IPC1480_00085, IPC1481_00290, IPC1482_30765, IPC1485_15035, IPC1486_32025, IPC1487_13215, IPC1488_20480, IPC148_17110, IPC1490_16870, IPC1491_19705, IPC1492_17070, IPC1494_21500, IPC1495_25750, IPC1496_11615, IPC1498_20020, IPC1499_09620, IPC149_25165, IPC1500_22370, IPC1501_13265, IPC1502_02780, IPC1503_18820, IPC1504_15800, IPC1505_27200, IPC1506_29575, IPC1507_17015, IPC1508_33650, IPC1509_32940, IPC150_17585, IPC1510_06650, IPC1511_32810, IPC1512_10570, IPC1513_12090, IPC1514_05245, IPC1515_24410, IPC1516_31195, IPC1517_12625, IPC1518_28865, IPC1519_29065, IPC151_14900, IPC1520_12605, IPC1521_31260, IPC1522_29465, IPC1523_15680, IPC152_18685, IPC153_18745, IPC154_12315, IPC155_15830, IPC156_07990, IPC157_13435, IPC1583_15930, IPC1584_13450, IPC1585_12565, IPC1586_18195, IPC1587_27960, IPC1588_13305, IPC1589_28890, IPC158_12390, IPC1591_33120, IPC1592_14750, IPC1593_19505, IPC1594_16345, IPC1596_16785, IPC1597_13755, IPC1598_18230, IPC1599_15180, IPC159_12265, IPC1600_28100, IPC1601_15675, IPC1602_09405, IPC1604_17495, IPC1605_26675, IPC1606_23045, IPC161_15170, IPC168_16280, IPC172_22925, IPC173_14945, IPC174_17330, IPC176_14825, IPC177_04060, IPC178_16520, IPC179_06880, IPC180_23800, IPC181_10520, IPC182_15555, IPC183_25610, IPC184_21165, IPC26_16055, IPC29_09655, IPC30_17820, IPC31_23505, IPC32_15855, IPC33_04975, IPC34_14720, IPC35_12080, IPC36_04320, IPC37_15430, IPC38_20495, IPC40_15555, IPC41_11800, IPC42_12730, IPC43_00020, IPC44_24900, IPC45_09375, IPC46_07640, IPC47_03600, IPC48_08915, IPC49_15095, IPC50_24635, IPC51_09265, IPC54_22585, IPC55_18640, IPC56_19020, IPC57_17610, IPC58_09970, IPC596_20455, IPC597_17715, IPC598_14325, IPC599_19180, IPC59_11650, IPC600_14470, IPC601_17050, IPC602_14500, IPC603_19260, IPC604_15740, IPC605_10100, IPC606_18645, IPC607_06675, IPC608_10230, IPC609_31610, IPC60_29660, IPC610_28700, IPC611_28990, IPC612_32580, IPC613_31865, IPC614_32130, IPC615_10155, IPC616_04245, IPC618_09775, IPC61_13550, IPC620_12285, IPC621_06135, IPC622_30350, IPC623_17495, IPC624_08490, IPC625_16055, IPC627_15010, IPC629_29230, IPC630_27175, IPC632_03910, IPC633_29935, IPC634_10370, IPC64_22510, IPC65_14205, IPC66_01310, IPC67_07525, IPC68_31745, IPC71_14470, IPC72_14440, IPC737_29575, IPC73_08650, IPC74_00405, IPC75_06170, IPC76_29125, IPC77_28405, IPC78_12355, NCTC13621_00173, PAMH19_5306, phzR, qscR
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 4.2.2
Spacegroup: P212121
Unit cell:
a: 57.591Å b: 91.91Å c: 93.999Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.212 0.208 0.27
Expression system: Escherichia coli