6ca6

X-ray diffraction
2.43Å resolution

Crystal structure of PCT64_35S, a broadly neutralizing anti-HIV antibody.

Released:
Source organism: Homo sapiens
Entry authors: Murrell S, Wilson IA

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
PCT64_35S light chain Chains: A, L
Molecule details ›
Chains: A, L
Length: 214 amino acids
Theoretical weight: 23.53 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins
PCT64_35S heavy chain Chains: B, H
Molecule details ›
Chains: B, H
Length: 238 amino acids
Theoretical weight: 25.6 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

2 bound ligands:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-D
Spacegroup: P212121
Unit cell:
a: 96.776Å b: 98.132Å c: 100.563Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.204 0.201 0.245
Expression system: Homo sapiens