› 6bxr

X-ray diffraction
1.6Å resolution

Crystal structure of Toxoplasma gondii Mitochondrial Association Factor 1 B (MAF1B)

Released:
DOI: 10.2210/pdb6bxr/pdb
PDB entry 6bxr coloured by chain, front view.
PDB entry 6bxr coloured by chain, side view.
PDB entry 6bxr coloured by chain, top view.
Source organism: Toxoplasma gondii
Primary publication:
A Toxoplasma gondii locus required for the direct manipulation of host mitochondria has maintained multiple ancestral functions.
Blank ML, Parker ML, Ramaswamy R, Powell CJ, English ED, Adomako-Ankomah Y, Pernas LF, Workman SD, Boothroyd JC, Boulanger MJ, Boyle JP
Mol Microbiol 108 519-535 (2018)
PMID: 29505111

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-102933 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mitochondrial association factor 1 form b1 Chain: A
Molecule details ›
Chain: A
Length: 273 amino acids
Theoretical weight: 29.08 KDa
Source organism: Toxoplasma gondii
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A140H546 (Residues: 173-443; Coverage: 64%)
Gene names: MAF1, MAF1b1, TGRH88_000130

Ligands and Environments

3 bound ligands:
Ligand BR 11 x BR
Ligand NA 3 x NA
Ligand GOL 3 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08B1-1
Spacegroup: P212121
Unit cell:
a: 45.09Å b: 62.11Å c: 89.21Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.175 0.173 0.213
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Manipulation of Host Cell Organelles by Intracellular Pathogens.
Kellermann et al. (2021)
2 more

2 mentions without citation

A Toxoplasma gondii locus required for the direct manipulation of host mitochondria has maintained multiple ancestral functions.
Blank et al. (2018)
1 more