6bsz

X-ray diffraction
2.65Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Metabotropic glutamate receptor 8 Chains: A, B
Molecule details ›
Chains: A, B
Length: 479 amino acids
Theoretical weight: 53.52 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: O00222 (Residues: 37-514; Coverage: 55%)
  • Best match: O00222-3 (Residues: 37-453)
Gene names: GPRC1H, GRM8, MGLUR8
Sequence domains: Receptor family ligand binding region

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 31-ID
Spacegroup: I222
Unit cell:
a: 112.539Å b: 166.623Å c: 198.661Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.252 0.25 0.274
Expression system: Spodoptera frugiperda