Function and Biology

Crystal structure of RapA, a Swi2/Snf2 protein that recycles RNA polymerase during transcription

Source organism: Escherichia coli S88
Biochemical function: ATP-dependent chromatin remodeler activity
Biological process: replication fork processing
Cellular component: not assigned

Sequence families

Pfam Protein families (Pfam)
PF12137
Domain description: RNA polymerase recycling family C-terminal
Occurring in:
  1. RNA polymerase-associated protein RapA
The deposited structure of PDB entry 6bog contains 2 copies of Pfam domain PF12137 (RNA polymerase recycling family C-terminal) in RNA polymerase-associated protein RapA. Showing 1 copy in chain A.

PF00271
Domain description: Helicase conserved C-terminal domain
Occurring in:
  1. RNA polymerase-associated protein RapA
The deposited structure of PDB entry 6bog contains 2 copies of Pfam domain PF00271 (Helicase conserved C-terminal domain) in RNA polymerase-associated protein RapA. Showing 1 copy in chain A.

PF00176
Domain description: SNF2-related domain
Occurring in:
  1. RNA polymerase-associated protein RapA
The deposited structure of PDB entry 6bog contains 2 copies of Pfam domain PF00176 (SNF2-related domain) in RNA polymerase-associated protein RapA. Showing 1 copy in chain A.

PF18337
Domain description: RapA N-terminal Tudor like domain
Occurring in:
  1. RNA polymerase-associated protein RapA
The deposited structure of PDB entry 6bog contains 2 copies of Pfam domain PF18337 (RapA N-terminal Tudor like domain) in RNA polymerase-associated protein RapA. Showing 1 copy in chain A.

PF18339
Domain description: RapA N-terminal Tudor like domain 1
Occurring in:
  1. RNA polymerase-associated protein RapA
The deposited structure of PDB entry 6bog contains 2 copies of Pfam domain PF18339 (RapA N-terminal Tudor like domain 1) in RNA polymerase-associated protein RapA. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001650
Domain description: Helicase, C-terminal domain-like
Occurring in:
  1. RNA polymerase-associated protein RapA
IPR027417
Domain description: P-loop containing nucleoside triphosphate hydrolase
Occurring in:
  1. RNA polymerase-associated protein RapA
IPR014001
Domain description: Helicase superfamily 1/2, ATP-binding domain
Occurring in:
  1. RNA polymerase-associated protein RapA
IPR022737
Domain description: RNA polymerase recycling, bacterial, C-terminal
Occurring in:
  1. RNA polymerase-associated protein RapA
IPR000330
Domain description: SNF2, N-terminal
Occurring in:
  1. RNA polymerase-associated protein RapA
IPR038718
Domain description: SNF2-like, N-terminal domain superfamily
Occurring in:
  1. RNA polymerase-associated protein RapA
IPR040766
Domain description: RapA, N-terminal Tudor-like domain 2
Occurring in:
  1. RNA polymerase-associated protein RapA
IPR040765
Domain description: RapA, N-terminal Tudor like domain 1
Occurring in:
  1. RNA polymerase-associated protein RapA
IPR023949
Domain description: RNA polymerase-associated protein RapA
Occurring in:
  1. RNA polymerase-associated protein RapA

Structure domains

CATH CATH domains
3.40.50.10810
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Rossmann fold
Homology: Tandem AAA-ATPase domain
Occurring in:
  1. RNA polymerase-associated protein RapA
The deposited structure of PDB entry 6bog contains 2 copies of CATH domain 3.40.50.10810 (Rossmann fold) in RNA polymerase-associated protein RapA. Showing 1 copy in chain A.
6.10.140.1500
Class: Special
Architecture: Helix non-globular
Topology: Helix Hairpins
Homology: Helix Hairpins
Occurring in:
  1. RNA polymerase-associated protein RapA
The deposited structure of PDB entry 6bog contains 2 copies of CATH domain 6.10.140.1500 (Helix Hairpins) in RNA polymerase-associated protein RapA. Showing 1 copy in chain A.
3.30.360.80
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: Dihydrodipicolinate Reductase; domain 2
Homology: Dihydrodipicolinate Reductase; domain 2
Occurring in:
  1. RNA polymerase-associated protein RapA
The deposited structure of PDB entry 6bog contains 2 copies of CATH domain 3.30.360.80 (Dihydrodipicolinate Reductase; domain 2) in RNA polymerase-associated protein RapA. Showing 1 copy in chain A.
6.10.140.2230
Class: Special
Architecture: Helix non-globular
Topology: Helix Hairpins
Homology: Helix Hairpins
Occurring in:
  1. RNA polymerase-associated protein RapA
The deposited structure of PDB entry 6bog contains 2 copies of CATH domain 6.10.140.2230 (Helix Hairpins) in RNA polymerase-associated protein RapA. Showing 1 copy in chain A.
3.40.50.300
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Rossmann fold
Homology: P-loop containing nucleotide triphosphate hydrolases
Occurring in:
  1. RNA polymerase-associated protein RapA
The deposited structure of PDB entry 6bog contains 2 copies of CATH domain 3.40.50.300 (Rossmann fold) in RNA polymerase-associated protein RapA. Showing 1 copy in chain A.
2.30.30.930
Class: Mainly Beta
Architecture: Roll
Topology: SH3 type barrels.
Homology: SH3 type barrels.
Occurring in:
  1. RNA polymerase-associated protein RapA
The deposited structure of PDB entry 6bog contains 2 copies of CATH domain 2.30.30.930 (SH3 type barrels.) in RNA polymerase-associated protein RapA. Showing 1 copy in chain A.
2.30.30.140
Class: Mainly Beta
Architecture: Roll
Topology: SH3 type barrels.
Homology: SH3 type barrels.
Occurring in:
  1. RNA polymerase-associated protein RapA
The deposited structure of PDB entry 6bog contains 2 copies of CATH domain 2.30.30.140 (SH3 type barrels.) in RNA polymerase-associated protein RapA. Showing 1 copy in chain A.