6blx

X-ray diffraction
2.32Å resolution

Crystal structure of IAg7 in complex with insulin mimotope p8G9E

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-137525 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
H-2 class II histocompatibility antigen, A-D alpha chain Chain: A
Molecule details ›
Chain: A
Length: 183 amino acids
Theoretical weight: 20.91 KDa
Source organism: Mus musculus
Expression system: Trichoplusia ni
UniProt:
  • Canonical: P04228 (Residues: 26-208; Coverage: 79%)
Gene name: H2-Aa
Sequence domains:
Structure domains:
Ig-like domain-containing protein Chain: B
Molecule details ›
Chain: B
Length: 221 amino acids
Theoretical weight: 25.29 KDa
Source organism: Mus musculus
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q31135 (Residues: 21-217; Coverage: 77%)
Gene name: H2-Ab1
Sequence domains:
Structure domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: P21
Unit cell:
a: 39.347Å b: 112.626Å c: 62.176Å
α: 90° β: 107.36° γ: 90°
R-values:
R R work R free
0.17 0.168 0.22
Expression system: Trichoplusia ni