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Crystal structure of Acat5 thiolase from Ascaris suum in complex with coenzyme A

Source organism: Ascaris suum
Biochemical function: acyltransferase activity, transferring groups other than amino-acyl groups
Biological process: fatty acid beta-oxidation
Cellular component: mitochondrion

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GO terms

Sequence families

Pfam Protein families (Pfam)
PF02803
Domain description: Thiolase, C-terminal domain
Occurring in:
  1. Acetyl-CoA acetyltransferase A
The deposited structure of PDB entry 6bja contains 1 copy of Pfam domain PF02803 (Thiolase, C-terminal domain) in Acetyl-CoA acetyltransferase A. Showing 1 copy in chain A.

PF00108
Domain description: Thiolase, N-terminal domain
Occurring in:
  1. Acetyl-CoA acetyltransferase A
The deposited structure of PDB entry 6bja contains 1 copy of Pfam domain PF00108 (Thiolase, N-terminal domain) in Acetyl-CoA acetyltransferase A. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR002155
Domain description: Thiolase
Occurring in:
  1. Acetyl-CoA acetyltransferase A
IPR016039
Domain description: Thiolase-like
Occurring in:
  1. Acetyl-CoA acetyltransferase A
IPR020610
Domain description: Thiolase, active site
Occurring in:
  1. Acetyl-CoA acetyltransferase A
IPR020613
Domain description: Thiolase, conserved site
Occurring in:
  1. Acetyl-CoA acetyltransferase A
IPR020617
Domain description: Thiolase, C-terminal
Occurring in:
  1. Acetyl-CoA acetyltransferase A
IPR020615
Domain description: Thiolase, acyl-enzyme intermediate active site
Occurring in:
  1. Acetyl-CoA acetyltransferase A
IPR020616
Domain description: Thiolase, N-terminal
Occurring in:
  1. Acetyl-CoA acetyltransferase A

Structure domain

CATH CATH domain
3.40.47.10
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Peroxisomal Thiolase; Chain A, domain 1
Homology: Peroxisomal Thiolase; Chain A, domain 1
Occurring in:
  1. Acetyl-CoA acetyltransferase A
The deposited structure of PDB entry 6bja contains 2 copies of CATH domain 3.40.47.10 (Peroxisomal Thiolase; Chain A, domain 1) in Acetyl-CoA acetyltransferase A. Showing 2 copies in chain A.

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