X-ray diffraction
1.91Å resolution

The structure of human CamKII with bound inhibitor

Source organism: Mus musculus
Entry authors: Somoza JR, Villasenor AG

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Calcium/calmodulin-dependent protein kinase type II subunit delta Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 302 amino acids
Theoretical weight: 34.46 KDa
Source organism: Mus musculus
Expression system: Spodoptera frugiperda
  • Canonical: Q6PHZ2 (Residues: 3-301; Coverage: 60%)
Gene names: Camk2d, Kiaa4163
Sequence domains: Protein kinase domain
Structure domains: Phosphorylase Kinase; domain 1

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-D
Spacegroup: P1
Unit cell:
a: 54.25Å b: 67.57Å c: 82.84Å
α: 93.34° β: 92.93° γ: 90.11°
R R work R free
0.191 0.19 0.253
Expression system: Spodoptera frugiperda