X-ray diffraction
2.2Å resolution

Crystal structure of human DDX19B(AMPPNP)


Function and Biology Details

Reaction catalysed:
ATP + H(2)O = ADP + phosphate
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
ATP-dependent RNA helicase DDX19B Chains: A, B
Molecule details ›
Chains: A, B
Length: 430 amino acids
Theoretical weight: 48.66 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q9UMR2 (Residues: 54-479; Coverage: 89%)
Gene names: DBP5, DDX19, DDX19B, TDBP
Sequence domains:
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-D
Spacegroup: P21
Unit cell:
a: 83.233Å b: 45.364Å c: 127.391Å
α: 90° β: 97.03° γ: 90°
R R work R free
0.209 0.207 0.248
Expression system: Escherichia coli