6b3v

X-ray diffraction
1.6Å resolution

PANK3 complex with compound PZ-2891

Released:

Function and Biology Details

Reaction catalysed:
ATP + (R)-pantothenate = ADP + (R)-4'-phosphopantothenate
Biochemical function:
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Pantothenate kinase 3 Chain: A
Molecule details ›
Chain: A
Length: 380 amino acids
Theoretical weight: 42.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9H999 (Residues: 12-370; Coverage: 97%)
Gene name: PANK3
Sequence domains: Fumble
Structure domains:

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P3121
Unit cell:
a: 98.874Å b: 98.874Å c: 69.117Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.178 0.178 0.195
Expression system: Escherichia coli BL21(DE3)