X-ray diffraction
3.2Å resolution

Function and Biology Details

Reactions catalysed:
5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] + H(2)O = N(7)-methylguanosine 5'-diphosphate + 5'-phospho-[mRNA]
IDP + H(2)O = IMP + phosphate

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
U8 snoRNA-decapping enzyme Chains: A, B
Molecule details ›
Chains: A, B
Length: 195 amino acids
Theoretical weight: 21.33 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q96DE0 (Residues: 1-195; Coverage: 100%)
  • Best match: Q96DE0-3 (Residues: 1-128)
Gene name: NUDT16
Sequence domains: NUDIX domain

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E+ DW
Spacegroup: C2
Unit cell:
a: 113.395Å b: 47.063Å c: 75.792Å
α: 90° β: 108.74° γ: 90°
R R work R free
0.257 0.256 0.279
Expression system: Escherichia coli