› 6ax2

Solution NMR

Solution structure of Magi3 a specific insect toxin from the spider Macrothele gigas

Released:
DOI: 10.2210/pdb6ax2/pdb
PDB entry 6ax2 coloured by chain, ensemble of 12 models, front view.
PDB entry 6ax2 coloured by chain, ensemble of 12 models, side view.
PDB entry 6ax2 coloured by chain, ensemble of 12 models, top view.
Source organism: Macrothele gigas
Primary publication:
Successful refolding and NMR structure of rMagi3: A disulfide-rich insecticidal spider toxin.
Titaux-Delgado G, Carrillo E, Mendoza A, Mayorga-Flores M, Escobedo-González FC, Cano-Sánchez P, López-Vera E, Corzo G, Del Rio-Portilla F
Protein Sci 27 692-701 (2018)
PMID: 29247580

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160707 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mu-hexatoxin-Mg2a Chain: A
Molecule details ›
Chain: A
Length: 46 amino acids
Theoretical weight: 5.24 KDa
Source organism: Macrothele gigas
Expression system: Escherichia coli
UniProt:
  • Canonical: P83559 (Residues: 1-46; Coverage: 100%)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 44%
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Scorpion Peptides and Ion Channels: An Insightful Review of Mechanisms and Drug Development.
Mendes et al. (2023)
1 more

2 mentions without citation

New Insectotoxin from Tibellus Oblongus Spider Venom Presents Novel Adaptation of ICK Fold.
Korolkova et al. (2021)
1 more