6avn

X-ray diffraction
2.5Å resolution

Crystal structure of unbound anti-HIV antibody Fab PGV19 at 2.5 A

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
PGV19 Fab heavy chain Chain: H
Molecule details ›
Chain: H
Length: 223 amino acids
Theoretical weight: 24.25 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins
PGV19 Fab light chain Chain: L
Molecule details ›
Chain: L
Length: 209 amino acids
Theoretical weight: 22.22 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-B
Spacegroup: P43212
Unit cell:
a: 69.783Å b: 69.783Å c: 193.28Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.201 0.199 0.25
Expression system: Homo sapiens