Assemblies
Assembly Name:
DNA-directed RNA polymerase and RNA and DNA
Multimeric state:
hetero octamer
Accessible surface area:
149555.82 Å2
Buried surface area:
39741.03 Å2
Dissociation area:
3,398.72
Å2
Dissociation energy (ΔGdiss):
30.67
kcal/mol
Dissociation entropy (TΔSdiss):
14.7
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-119586
Macromolecules
Chains: G, H
Length: 239 amino acids
Theoretical weight: 26.46 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
Pfam:
InterPro:
Length: 239 amino acids
Theoretical weight: 26.46 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
- Canonical: P0A7Z4 (Residues: 1-234; Coverage: 71%)
Pfam:
InterPro:
- RNA polymerase, RBP11-like subunit
- DNA-directed RNA polymerase, RpoA/D/Rpb3-type
- DNA-directed RNA polymerase, alpha subunit
- DNA-directed RNA polymerase, insert domain superfamily
- DNA-directed RNA polymerase, insert domain
Chain: I
Length: 1342 amino acids
Theoretical weight: 150.82 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
Pfam:
Length: 1342 amino acids
Theoretical weight: 150.82 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
- Canonical: P0A8V2 (Residues: 1-1342; Coverage: 100%)
Pfam:
- RNA polymerase beta subunit
- RNA polymerase Rpb2, domain 2
- RNA polymerase Rpb2, domain 3
- RNA polymerase beta subunit external 1 domain
- RNA polymerase Rpb2, domain 6
- RNA polymerase Rpb2, domain 7
- DNA-directed RNA polymerase beta subunit, bacterial-type
- RNA polymerase, beta subunit, protrusion
- DNA-directed RNA polymerase, subunit 2
- RNA polymerase Rpb2, domain 2
- RNA polymerase Rpb2, domain 2 superfamily
- RNA polymerase Rpb2, domain 3
- DNA-directed RNA polymerase, beta subunit, external 1 domain superfamily
- DNA-directed RNA polymerase, beta subunit, external 1 domain
- DNA-directed RNA polymerase, subunit 2, hybrid-binding domain
- RNA polymerase Rpb2, OB-fold
- DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily
- RNA polymerase, beta subunit, conserved site
- RNA polymerase Rpb2, domain 7
Chain: J
Length: 1407 amino acids
Theoretical weight: 155.37 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
Pfam:
Length: 1407 amino acids
Theoretical weight: 155.37 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
- Canonical: P0A8T7 (Residues: 1-1407; Coverage: 100%)
Pfam:
- RNA polymerase Rpb1, domain 1
- RNA polymerase Rpb1, domain 2
- RNA polymerase Rpb1, domain 3
- RNA polymerase Rpb1, domain 4
- RNA polymerase Rpb1, domain 5
- RNA polymerase Rpb1, clamp domain superfamily
- DNA-directed RNA polymerase, subunit beta-prime, bacterial type
- RNA polymerase Rpb1, domain 1
- DNA-directed RNA polymerase, subunit beta-prime
- RNA polymerase, N-terminal
- RNA polymerase, alpha subunit
- RNA polymerase Rpb1, domain 3
- RNA polymerase Rpb1, domain 3 superfamily
- RNA polymerase Rpb1, funnel domain superfamily
- RNA polymerase Rpb1, domain 4
- RNA polymerase Rpb1, domain 5
Chain: K
Length: 84 amino acids
Theoretical weight: 9.49 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
Pfam: RNA polymerase Rpb6
InterPro:
Length: 84 amino acids
Theoretical weight: 9.49 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli
UniProt:
- Canonical: P0A800 (Residues: 1-84; Coverage: 92%)
Pfam: RNA polymerase Rpb6
InterPro:
- DNA-directed RNA polymerase, omega subunit
- RPB6/omega subunit-like superfamily
- RNA polymerase, subunit omega/Rpo6/RPB6