PDBe 6asa

X-ray diffraction
2.54Å resolution

KRAS mutant-D33E in GDP-bound

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
GTPase KRas, N-terminally processed Chain: A
Molecule details ›
Chain: A
Length: 168 amino acids
Theoretical weight: 19.16 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P01116 (Residues: 1-167; Coverage: 88%)
  • Best match: P01116-2 (Residues: 1-168)
Gene names: KRAS, KRAS2, RASK2
Sequence domains: Ras family

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P212121
Unit cell:
a: 34.527Å b: 47.075Å c: 90.765Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.194 0.186 0.264
Expression system: Escherichia coli