6aoq

X-ray diffraction
2.35Å resolution

Crystal structure of the A/Brisbane/10/2007 (H3N2) influenza virus hemagglutinin apo form

Released:
Entry authors: Wu NC, Wilson IA

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (5 distinct):
Hemagglutinin Chain: A
Molecule details ›
Chain: A
Length: 323 amino acids
Theoretical weight: 35.92 KDa
Source organism: Influenza A virus (A/Brisbane/10/2007(H3N2))
Expression system: Trichoplusia ni
UniProt:
  • Canonical: B2VNK2 (Residues: 11-329; Coverage: 96%)
Gene name: HA
Sequence domains: Haemagglutinin
Structure domains: Hemagglutinin (Ha1 Chain); Chain: A; domain 1
Hemagglutinin Chain: B
Molecule details ›
Chain: B
Length: 174 amino acids
Theoretical weight: 19.95 KDa
Source organism: Influenza A virus (A/Brisbane/10/2007(H3N2))
Expression system: Trichoplusia ni
UniProt:
  • Canonical: C3PR70 (Residues: 346-519; Coverage: 31%)
Gene name: HA
Sequence domains: Haemagglutinin
Structure domains: Hemagglutinin Ectodomain; Chain B

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer : NEW Components: NAG
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL12-2
Spacegroup: R32
Unit cell:
a: 100.614Å b: 100.614Å c: 382.62Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.218 0.216 0.262
Expression system: Trichoplusia ni