Assemblies
Assembly Name:
Tyrosine-protein kinase JAK3
Multimeric state:
homo dimer
Accessible surface area:
26092.43 Å2
Buried surface area:
1264.69 Å2
Dissociation area:
632.34
Å2
Dissociation energy (ΔGdiss):
-5.08
kcal/mol
Dissociation entropy (TΔSdiss):
12.91
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-156549
Assembly Name:
Tyrosine-protein kinase JAK3
Multimeric state:
homo dimer
Accessible surface area:
25423.38 Å2
Buried surface area:
1164.14 Å2
Dissociation area:
582.07
Å2
Dissociation energy (ΔGdiss):
-3.93
kcal/mol
Dissociation entropy (TΔSdiss):
12.81
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-156549
Macromolecules
Chains: A, B, C, D
Length: 287 amino acids
Theoretical weight: 32.86 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Pfam: Protein tyrosine and serine/threonine kinase
InterPro:
Length: 287 amino acids
Theoretical weight: 32.86 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical:
P52333 (Residues: 814-1100; Coverage: 26%)
Pfam: Protein tyrosine and serine/threonine kinase
InterPro:
- Protein kinase-like domain superfamily
- Protein kinase domain
- Tyrosine-protein kinase, catalytic domain
- Serine-threonine/tyrosine-protein kinase, catalytic domain
- Protein kinase, ATP binding site
- Tyrosine-protein kinase, active site
