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Human antibody 32D6 Fab in complex with H1N1 influenza A virus HA1

Source organisms:
Biochemical function: host cell surface receptor binding
Biological process: fusion of virus membrane with host plasma membrane
Cellular component: viral envelope

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GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence family

Pfam Protein family (Pfam)
PF00509
Domain description: Haemagglutinin
Occurring in:
  1. Hemagglutinin
The deposited structure of PDB entry 6a4k contains 4 copies of Pfam domain PF00509 (Haemagglutinin) in Hemagglutinin. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR000149
Domain description: Haemagglutinin, influenzavirus A
Occurring in:
  1. Hemagglutinin
IPR003597
Domain description: Immunoglobulin C1-set
Occurring in:
  1. immunoglobulin Fab heavy chain
  2. immunoglobulin Fab light chain
IPR013106
Domain description: Immunoglobulin V-set domain
Occurring in:
  1. immunoglobulin Fab heavy chain
  2. immunoglobulin Fab light chain
IPR036179
Domain description: Immunoglobulin-like domain superfamily
Occurring in:
  1. immunoglobulin Fab heavy chain
  2. immunoglobulin Fab light chain
IPR013783
Domain description: Immunoglobulin-like fold
Occurring in:
  1. immunoglobulin Fab heavy chain
  2. immunoglobulin Fab light chain
IPR007110
Domain description: Immunoglobulin-like domain
Occurring in:
  1. immunoglobulin Fab heavy chain
  2. immunoglobulin Fab light chain
IPR003599
Domain description: Immunoglobulin subtype
Occurring in:
  1. immunoglobulin Fab heavy chain
  2. immunoglobulin Fab light chain
IPR003006
Domain description: Immunoglobulin/major histocompatibility complex, conserved site
Occurring in:
  1. immunoglobulin Fab heavy chain
  2. immunoglobulin Fab light chain
IPR008980
Domain description: Viral capsid/haemagglutinin protein
Occurring in:
  1. Hemagglutinin
IPR013828
Domain description: Haemagglutinin, HA1 chain, alpha/beta domain superfamily
Occurring in:
  1. Hemagglutinin
IPR001364
Domain description: Haemagglutinin, influenzavirus A/B
Occurring in:
  1. Hemagglutinin

Structure domains

CATH CATH domains
2.60.40.10
Class: Mainly Beta
Architecture: Sandwich
Topology: Immunoglobulin-like
Homology: Immunoglobulins
Occurring in:
  1. immunoglobulin Fab light chain
The deposited structure of PDB entry 6a4k contains 4 copies of CATH domain 2.60.40.10 (Immunoglobulin-like) in immunoglobulin Fab light chain. Showing 1 copy in chain C [auth L].
3.90.209.20
Class: Alpha Beta
Architecture: Alpha-Beta Complex
Topology: Hemagglutinin (Ha1 Chain); Chain: A; domain 1
Homology: Hemagglutinin (Ha1 Chain); Chain: A; domain 1
Occurring in:
  1. Hemagglutinin
The deposited structure of PDB entry 6a4k contains 4 copies of CATH domain 3.90.209.20 (Hemagglutinin (Ha1 Chain); Chain: A; domain 1) in Hemagglutinin. Showing 1 copy in chain A.

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