6a4k

X-ray diffraction
3.15Å resolution

Human antibody 32D6 Fab in complex with H1N1 influenza A virus HA1

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Hemagglutinin Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 235 amino acids
Theoretical weight: 26.41 KDa
Source organism: Influenza A virus (A/California/7/2009(H1N1))
Expression system: Homo sapiens
UniProt:
  • Canonical: C3W5X2 (Residues: 63-290; Coverage: 40%)
Gene name: HA
Sequence domains: Haemagglutinin
Structure domains: Hemagglutinin (Ha1 Chain); Chain: A; domain 1
immunoglobulin Fab heavy chain Chains: H, I, J, K
Molecule details ›
Chains: H, I, J, K
Length: 238 amino acids
Theoretical weight: 25.56 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
immunoglobulin Fab light chain Chains: L, M, N, O
Molecule details ›
Chains: L, M, N, O
Length: 216 amino acids
Theoretical weight: 23.01 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSRRC BEAMLINE TPS 05A
Spacegroup: P3112
Unit cell:
a: 181.743Å b: 181.743Å c: 248.091Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.178 0.175 0.233
Expression system: Homo sapiens