› 6zvk

Electron Microscopy
3.49Å resolution

The Halastavi arva virus (HalV) intergenic region IRES promotes translation by the simplest possible initiation mechanism

Released:
DOI: 10.2210/pdb6zvk/pdb
PDB entry 6zvk coloured by chain, front view.
PDB entry 6zvk coloured by chain, side view.
PDB entry 6zvk coloured by chain, top view.
Source organism: Oryctolagus cuniculus
Primary publication:
The Halastavi árva Virus Intergenic Region IRES Promotes Translation by the Simplest Possible Initiation Mechanism.
Abaeva IS, Vicens Q, Bochler A, Soufari H, Simonetti A, Pestova TV, Hashem Y, Hellen CUT
Cell Rep 33 108476 (2020)
PMID: 33296660
Related structures: EMD-11459

Function and Biology Details

Reaction catalysed: 
The C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero 85-mer (preferred)
PDBe Complex ID:
PDB-CPX-242941 (preferred)
Entry contents:
80 distinct polypeptide molecules
5 distinct RNA molecules
Macromolecules (85 distinct):
Ribosomal protein L14 Chain: Z2
Molecule details ›
Chain: Z2
Length: 138 amino acids
Theoretical weight: 16.22 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: U3KNW6 (Residues: 2-139; Coverage: 63%)
Sequence domains: Ribosomal protein L14
Large ribosomal subunit protein eL38 Chain: p2
Molecule details ›
Chain: p2
Length: 69 amino acids
Theoretical weight: 8.09 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1U001 (Residues: 2-70; Coverage: 99%)
Gene name: RPL38
Sequence domains: Ribosomal L38e protein family
Large ribosomal subunit protein uL13 Chain: w2
Molecule details ›
Chain: w2
Length: 199 amino acids
Theoretical weight: 23.14 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G5B8P1 (Residues: 1-199; Coverage: 100%)
Gene name: GW7_15288
Sequence domains: Ribosomal protein L13
uL22 Chain: H2
Molecule details ›
Chain: H2
Length: 153 amino acids
Theoretical weight: 17.76 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TVT6 (Residues: 2-183; Coverage: 72%)
Sequence domains: Ribosomal protein L22p/L17e
Large ribosomal subunit protein eL18 Chain: S2
Molecule details ›
Chain: S2
Length: 187 amino acids
Theoretical weight: 21.56 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: Q07020 (Residues: 2-188; Coverage: 100%)
Gene name: RPL18
Sequence domains: Ribosomal protein 60S L18 and 50S L18e
Large ribosomal subunit protein eL19 Chain: 32
Molecule details ›
Chain: 32
Length: 180 amino acids
Theoretical weight: 21.61 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: Q3T0W9 (Residues: 2-181; Coverage: 92%)
Gene name: RPL19
Sequence domains: Ribosomal protein L19e
Large ribosomal subunit protein uL3 Chain: 52
Molecule details ›
Chain: 52
Length: 394 amino acids
Theoretical weight: 45.12 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TL06 (Residues: 2-395; Coverage: 98%)
Gene name: RPL3
Sequence domains: Ribosomal protein L3
Large ribosomal subunit protein eL20 Chain: 62
Molecule details ›
Chain: 62
Length: 175 amino acids
Theoretical weight: 20.68 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: Q3T003 (Residues: 2-176; Coverage: 99%)
Gene name: RPL18A
Sequence domains: Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A
Large ribosomal subunit protein eL21 Chain: 72
Molecule details ›
Chain: 72
Length: 159 amino acids
Theoretical weight: 18.48 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SHQ2 (Residues: 2-160; Coverage: 99%)
Gene name: RPL21
Sequence domains: Ribosomal protein L21e
Large ribosomal subunit protein eL22 Chain: 82
Molecule details ›
Chain: 82
Length: 99 amino acids
Theoretical weight: 11.48 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TSG1 (Residues: 17-115; Coverage: 77%)
Gene name: RPL22
Sequence domains: Ribosomal L22e protein family
Large ribosomal subunit protein uL14 Chain: k2
Molecule details ›
Chain: k2
Length: 131 amino acids
Theoretical weight: 13.97 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1T6D1 (Residues: 10-140; Coverage: 94%)
Gene name: RPL23
Sequence domains: Ribosomal protein L14p/L23e
Large ribosomal subunit protein eL24 Chain: l2
Molecule details ›
Chain: l2
Length: 63 amino acids
Theoretical weight: 7.51 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SE28 (Residues: 1-63; Coverage: 40%)
Gene name: RPL24
Sequence domains: Ribosomal protein L24e
Large ribosomal subunit protein uL23 Chain: m2
Molecule details ›
Chain: m2
Length: 119 amino acids
Theoretical weight: 13.86 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SE76 (Residues: 38-156; Coverage: 76%)
Gene name: RPL23A
Sequence domains:
Large ribosomal subunit protein uL24 Chain: o2
Molecule details ›
Chain: o2
Length: 134 amino acids
Theoretical weight: 15.89 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SQH0 (Residues: 1-134; Coverage: 92%)
Gene name: RPL26
Sequence domains:
Large ribosomal subunit protein uL15 Chain: q2
Molecule details ›
Chain: q2
Length: 147 amino acids
Theoretical weight: 16.49 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SNY0 (Residues: 2-148; Coverage: 99%)
Gene name: RPL27A
Sequence domains: Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
60S ribosomal protein L29 Chain: r2
Molecule details ›
Chain: r2
Length: 75 amino acids
Theoretical weight: 8.71 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TN82 (Residues: 2-76; Coverage: 34%)
Sequence domains: Ribosomal L29e protein family
Large ribosomal subunit protein eL30 Chain: 13
Molecule details ›
Chain: 13
Length: 94 amino acids
Theoretical weight: 10.5 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TDL2 (Residues: 13-106; Coverage: 82%)
Gene name: RPL30
Sequence domains: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
Large ribosomal subunit protein uL4 Chain: t2
Molecule details ›
Chain: t2
Length: 362 amino acids
Theoretical weight: 41.1 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SVW5 (Residues: 2-363; Coverage: 88%)
Gene name: RPL4
Sequence domains:
Large ribosomal subunit protein eL31 Chain: u2
Molecule details ›
Chain: u2
Length: 107 amino acids
Theoretical weight: 12.64 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SHG0 (Residues: 18-124; Coverage: 86%)
Gene name: RPL31
Sequence domains: Ribosomal protein L31e
Large ribosomal subunit protein eL32 Chain: v2
Molecule details ›
Chain: v2
Length: 128 amino acids
Theoretical weight: 15.02 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TUN8 (Residues: 24-151; Coverage: 82%)
Gene name: RPL32
Sequence domains: Ribosomal protein L32
Large ribosomal subunit protein eL33 Chain: x2
Molecule details ›
Chain: x2
Length: 109 amino acids
Theoretical weight: 12.45 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SF08 (Residues: 2-110; Coverage: 99%)
Gene name: RPL35A
Sequence domains: Ribosomal protein L35Ae
eL34 Chain: y2
Molecule details ›
Chain: y2
Length: 114 amino acids
Theoretical weight: 12.99 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1U945 (Residues: 14-127; Coverage: 88%)
Sequence domains: Ribosomal protein L34e
Large ribosomal subunit protein uL2 Chain: 92
Molecule details ›
Chain: 92
Length: 244 amino acids
Theoretical weight: 26.57 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TT27 (Residues: 2-217; Coverage: 85%)
Gene name: RPL8
Sequence domains:
Large ribosomal subunit protein uL29 Chain: A2
Molecule details ›
Chain: A2
Length: 122 amino acids
Theoretical weight: 14.44 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SIT5 (Residues: 2-123; Coverage: 99%)
Gene name: RPL35
Sequence domains: Ribosomal L29 protein
Large ribosomal subunit protein eL36 Chain: B2
Molecule details ›
Chain: B2
Length: 102 amino acids
Theoretical weight: 11.89 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TTQ5 (Residues: 26-97; Coverage: 73%)
Gene name: RPL36
Sequence domains: Ribosomal protein L36e
Large ribosomal subunit protein eL37 Chain: C2
Molecule details ›
Chain: C2
Length: 86 amino acids
Theoretical weight: 10.09 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: U3KPD5 (Residues: 2-87; Coverage: 89%)
Gene name: RPL37
Sequence domains: Ribosomal protein L37e
Large ribosomal subunit protein eL39 Chain: D2
Molecule details ›
Chain: D2
Length: 50 amino acids
Theoretical weight: 6.3 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SYU7 (Residues: 2-51; Coverage: 98%)
Gene name: RPL39
Sequence domains: Ribosomal L39 protein
Large ribosomal subunit protein eL40 Chain: E2
Molecule details ›
Chain: E2
Length: 52 amino acids
Theoretical weight: 6.2 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: P63048 (Residues: 77-128; Coverage: 41%)
Gene names: UBA52, UBCEP2
Sequence domains: Ribosomal L40e family
Large ribosomal subunit protein eL42 Chain: F2
Molecule details ›
Chain: F2
Length: 104 amino acids
Theoretical weight: 12.2 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1T040 (Residues: 2-100; Coverage: 89%)
Gene name: RPL36A
Sequence domains: Ribosomal protein L44
Large ribosomal subunit protein uL18 C-terminal eukaryotes domain-containing protein Chain: G2
Molecule details ›
Chain: G2
Length: 292 amino acids
Theoretical weight: 34.01 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SYJ6 (Residues: 3-294; Coverage: 98%)
Sequence domains:
Large ribosomal subunit protein eL43 Chain: I2
Molecule details ›
Chain: I2
Length: 91 amino acids
Theoretical weight: 10.17 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SY53 (Residues: 2-92; Coverage: 99%)
Gene name: RPL37A
Sequence domains: Ribosomal L37ae protein family
Large ribosomal subunit protein eL28 Chain: J2
Molecule details ›
Chain: J2
Length: 125 amino acids
Theoretical weight: 14.32 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1U7L1 (Residues: 2-126; Coverage: 91%)
Gene name: RPL28
Sequence domains: Ribosomal L28e protein family
Large ribosomal subunit protein uL10 Chain: K2
Molecule details ›
Chain: K2
Length: 198 amino acids
Theoretical weight: 21.75 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SPK4 (Residues: 5-202; Coverage: 62%)
Gene name: RPLP0
Sequence domains:
Large ribosomal subunit protein uL16 Chain: L2
Molecule details ›
Chain: L2
Length: 102 amino acids
Theoretical weight: 11.94 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: B7NZQ2 (Residues: 2-103; Coverage: 48%)
Gene name: RPL10
Sequence domains: Ribosomal protein L16p/L10e
Large ribosomal subunit protein uL11 Chain: M2
Molecule details ›
Chain: M2
Length: 163 amino acids
Theoretical weight: 17.68 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SMR7 (Residues: 1-163; Coverage: 99%)
Gene name: RPL12
Sequence domains:
Large ribosomal subunit protein eL6 Chain: R2
Molecule details ›
Chain: R2
Length: 35 amino acids
Theoretical weight: 4.06 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1U1N5 (Residues: 139-173; Coverage: 9%)
Sequence domains: Ribosomal protein L6, N-terminal domain
Large ribosomal subunit protein eL6 Chain: T2
Molecule details ›
Chain: T2
Length: 201 amino acids
Theoretical weight: 22.88 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SKF7 (Residues: 91-291; Coverage: 69%)
Gene name: RPL6
Sequence domains: Ribosomal protein L6e
Large ribosomal subunit protein uL30 Chain: U2
Molecule details ›
Chain: U2
Length: 225 amino acids
Theoretical weight: 26.66 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SV32 (Residues: 25-249; Coverage: 90%)
Gene name: RPL7
Sequence domains:
Large ribosomal subunit protein eL8 Chain: V2
Molecule details ›
Chain: V2
Length: 241 amino acids
Theoretical weight: 27.45 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: P62424 (Residues: 26-266; Coverage: 91%)
Gene names: RPL7A, SURF-3, SURF3
Sequence domains: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
Large ribosomal subunit protein uL6 Chain: W2
Molecule details ›
Chain: W2
Length: 190 amino acids
Theoretical weight: 21.63 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SWI6 (Residues: 1-190; Coverage: 99%)
Gene name: RPL9
Sequence domains: Ribosomal protein L6
Large ribosomal subunit protein uL16 Chain: X2
Molecule details ›
Chain: X2
Length: 102 amino acids
Theoretical weight: 11.68 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: B7NZQ2 (Residues: 113-214; Coverage: 48%)
Gene name: RPL10
Sequence domains: Ribosomal protein L16p/L10e
Large ribosomal subunit protein uL5 Chain: Y2
Molecule details ›
Chain: Y2
Length: 169 amino acids
Theoretical weight: 19.27 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TUB8 (Residues: 9-177; Coverage: 95%)
Gene name: RPL11
Sequence domains:
60S ribosomal protein L13 Chain: a7
Molecule details ›
Chain: a7
Length: 210 amino acids
Theoretical weight: 24.2 KDa
Source organism: Oryctolagus cuniculus
Large ribosomal subunit protein eL15 Chain: 12
Molecule details ›
Chain: 12
Length: 203 amino acids
Theoretical weight: 24.08 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1T0C1 (Residues: 2-204; Coverage: 100%)
Gene name: RPL15
Sequence domains: Ribosomal L15
Large ribosomal subunit protein eL27 Chain: 22
Molecule details ›
Chain: 22
Length: 135 amino acids
Theoretical weight: 15.7 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TXF6 (Residues: 2-136; Coverage: 99%)
Gene name: RPL27
Sequence domains:
Large ribosomal subunit protein uL1 Chain: 42
Molecule details ›
Chain: 42
Length: 217 amino acids
Theoretical weight: 24.88 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SKZ8 (Residues: 1-217; Coverage: 100%)
Gene name: RPL10A
Sequence domains: Ribosomal protein L1p/L10e family
Small ribosomal subunit protein uS10 Chain: I3
Molecule details ›
Chain: I3
Length: 104 amino acids
Theoretical weight: 11.77 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: A0A5F9CX53 (Residues: 16-119; Coverage: 87%)
Sequence domains: Ribosomal protein S10p/S20e
Small ribosomal subunit protein eS30 Chain: s3
Molecule details ›
Chain: s3
Length: 43 amino acids
Theoretical weight: 5.01 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: P62866 (Residues: 2-44; Coverage: 73%)
Gene name: FAU
Sequence domains: Ribosomal protein S30
Small ribosomal subunit protein uS17 Chain: G3
Molecule details ›
Chain: G3
Length: 153 amino acids
Theoretical weight: 17.79 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TRM4 (Residues: 2-154; Coverage: 97%)
Gene name: RPS11
Sequence domains:
Small ribosomal subunit protein eS28 Chain: f3
Molecule details ›
Chain: f3
Length: 64 amino acids
Theoretical weight: 7.26 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TIB4 (Residues: 5-68; Coverage: 93%)
Gene name: RPS28
Sequence domains: Ribosomal protein S28e
Small ribosomal subunit protein eS7 Chain: P3
Molecule details ›
Chain: P3
Length: 189 amino acids
Theoretical weight: 21.6 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: A6H769 (Residues: 5-193; Coverage: 97%)
Gene name: RPS7
Sequence domains: Ribosomal protein S7e
Small ribosomal subunit protein uS11 Chain: a5
Molecule details ›
Chain: a5
Length: 136 amino acids
Theoretical weight: 14.54 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1T1F0 (Residues: 16-151; Coverage: 90%)
Gene name: RPS14
Sequence domains: Ribosomal protein S11
Small ribosomal subunit protein uS19 Chain: A3
Molecule details ›
Chain: A3
Length: 127 amino acids
Theoretical weight: 15.15 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1U0Q2 (Residues: 4-130; Coverage: 88%)
Gene name: RPS15
Sequence domains: Ribosomal protein S19
Small ribosomal subunit protein uS9 Chain: B3
Molecule details ›
Chain: B3
Length: 141 amino acids
Theoretical weight: 15.98 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SGX4 (Residues: 32-172; Coverage: 82%)
Gene name: RPS16
Sequence domains: Ribosomal protein S9/S16
Small ribosomal subunit protein eS17 Chain: C3
Molecule details ›
Chain: C3
Length: 129 amino acids
Theoretical weight: 14.97 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TU13 (Residues: 1-129; Coverage: 96%)
Gene name: RPS17
Sequence domains: Ribosomal S17
Small ribosomal subunit protein eS21 Chain: D3
Molecule details ›
Chain: D3
Length: 83 amino acids
Theoretical weight: 9.04 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: A0A1Z5KTU7 (Residues: 1-83; Coverage: 100%)
Sequence domains: Ribosomal protein S21e
Small ribosomal subunit protein uS13 Chain: G5
Molecule details ›
Chain: G5
Length: 137 amino acids
Theoretical weight: 16.17 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TPG3 (Residues: 6-142; Coverage: 90%)
Gene name: RPS18
Sequence domains: Ribosomal protein S13/S18
Small ribosomal subunit protein eS19 Chain: H5
Molecule details ›
Chain: H5
Length: 141 amino acids
Theoretical weight: 15.81 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TN62 (Residues: 4-144; Coverage: 97%)
Gene name: RPS19
Sequence domains: Ribosomal protein S19e
Small ribosomal subunit protein uS8 Chain: J5
Molecule details ›
Chain: J5
Length: 129 amino acids
Theoretical weight: 14.73 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TG89 (Residues: 2-130; Coverage: 99%)
Gene name: RPS15A
Sequence domains: Ribosomal protein S8
40S ribosomal protein S24 Chain: I5
Molecule details ›
Chain: I5
Length: 126 amino acids
Theoretical weight: 14.6 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: A0A5F9CBF4 (Residues: 3-128; Coverage: 97%)
Sequence domains: Ribosomal protein S24e
Small ribosomal subunit protein eS27 Chain: L3
Molecule details ›
Chain: L3
Length: 83 amino acids
Theoretical weight: 9.35 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TZ76 (Residues: 2-84; Coverage: 99%)
Gene name: RPS27
Sequence domains: Ribosomal protein S27
Small ribosomal subunit protein eS25 Chain: M3
Molecule details ›
Chain: M3
Length: 75 amino acids
Theoretical weight: 8.53 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TDB3 (Residues: 40-114; Coverage: 61%)
Gene name: RPS25
Sequence domains: S25 ribosomal protein
Small ribosomal subunit protein eS26 Chain: O3
Molecule details ›
Chain: O3
Length: 98 amino acids
Theoretical weight: 11.18 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: Q56JV1 (Residues: 2-99; Coverage: 85%)
Gene name: RPS26
Sequence domains: Ribosomal protein S26e
Small ribosomal subunit protein eS31 Chain: Q3
Molecule details ›
Chain: Q3
Length: 69 amino acids
Theoretical weight: 8.11 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: P79781 (Residues: 83-151; Coverage: 44%)
Gene names: RPS27A, UBA80
Sequence domains: Ribosomal protein S27a
Small ribosomal subunit protein RACK1 Chain: a3
Molecule details ›
Chain: a3
Length: 313 amino acids
Theoretical weight: 34.67 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SJB4 (Residues: 117-421; Coverage: 72%)
Gene name: RACK1
Sequence domains: WD domain, G-beta repeat
Small ribosomal subunit protein uS12 Chain: T3
Molecule details ›
Chain: T3
Length: 141 amino acids
Theoretical weight: 15.63 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SZ47 (Residues: 2-142; Coverage: 99%)
Gene name: RPS23
Sequence domains: Ribosomal protein S12/S23
40S ribosomal protein SA Chain: U3
Molecule details ›
Chain: U3
Length: 208 amino acids
Theoretical weight: 23.39 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TJH8 (Residues: 2-209; Coverage: 74%)
Sequence domains: Ribosomal protein S2
Small ribosomal subunit protein eS1 Chain: V3
Molecule details ›
Chain: V3
Length: 213 amino acids
Theoretical weight: 24.76 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SS70 (Residues: 21-233; Coverage: 81%)
Gene name: RPS3A
Sequence domains: Ribosomal S3Ae family
S5 DRBM domain-containing protein Chain: W3
Molecule details ›
Chain: W3
Length: 218 amino acids
Theoretical weight: 24.09 KDa
Source organism: Oryctolagus cuniculus
Small ribosomal subunit protein eS32 Chain: X3
Molecule details ›
Chain: X3
Length: 23 amino acids
Theoretical weight: 3.21 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: A0A087WNH4 (Residues: 2-24; Coverage: 92%)
Gene name: RPL41
Sequence domains: Ribosomal protein L41
Small ribosomal subunit protein uS3 Chain: Y3
Molecule details ›
Chain: Y3
Length: 227 amino acids
Theoretical weight: 25.16 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TNM3 (Residues: 39-265; Coverage: 81%)
Gene name: RPS3
Sequence domains:
Small ribosomal subunit protein eS4 Chain: j3
Molecule details ›
Chain: j3
Length: 262 amino acids
Theoretical weight: 29.53 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TK17 (Residues: 2-263; Coverage: 100%)
Gene name: RPS4X
Sequence domains:
Small ribosomal subunit protein uS7 Chain: N3
Molecule details ›
Chain: N3
Length: 191 amino acids
Theoretical weight: 21.53 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: U3KMN4 (Residues: 29-219; Coverage: 87%)
Gene name: RPS5
Sequence domains: Ribosomal protein S7p/S5e
Small ribosomal subunit protein eS6 Chain: b3
Molecule details ›
Chain: b3
Length: 237 amino acids
Theoretical weight: 27.47 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TM55 (Residues: 11-211; Coverage: 81%)
Gene name: RPS6
Sequence domains: Ribosomal protein S6e
Small ribosomal subunit protein eS8 Chain: c3
Molecule details ›
Chain: c3
Length: 206 amino acids
Theoretical weight: 24 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TJW1 (Residues: 2-207; Coverage: 99%)
Gene name: RPS8
Sequence domains: Ribosomal protein S8e
Small ribosomal subunit protein uS4 Chain: d3
Molecule details ›
Chain: d3
Length: 185 amino acids
Theoretical weight: 21.65 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: B7NZS8 (Residues: 2-186; Coverage: 95%)
Gene name: RPS9
Sequence domains:
Small ribosomal subunit protein eS12 Chain: e3
Molecule details ›
Chain: e3
Length: 124 amino acids
Theoretical weight: 13.77 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SFR8 (Residues: 9-132; Coverage: 94%)
Gene name: RPS12
Sequence domains: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
Small ribosomal subunit protein uS15 Chain: F3
Molecule details ›
Chain: F3
Length: 150 amino acids
Theoretical weight: 17.13 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1SP51 (Residues: 11-152; Coverage: 92%)
Gene name: RPS13
Sequence domains:
Small ribosomal subunit protein eS10 Chain: E3
Molecule details ›
Chain: E3
Length: 98 amino acids
Theoretical weight: 11.77 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1T168 (Residues: 61-158; Coverage: 44%)
Gene name: RPS10
Sequence domains: Plectin/S10 domain
Small ribosomal subunit protein uS14 Chain: H3
Molecule details ›
Chain: H3
Length: 53 amino acids
Theoretical weight: 6.36 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1U7M4 (Residues: 4-56; Coverage: 95%)
Gene name: RPS29
Sequence domains: Ribosomal protein S14p/S29e
28S ribosomal RNA Chain: e2
Molecule details ›
Chain: e2
Length: 3920 nucleotides
Theoretical weight: 1269.66 KDa
Sequence domains: Eukaryotic large subunit ribosomal RNA
5S ribosomal RNA Chain: d2
Molecule details ›
Chain: d2
Length: 120 nucleotides
Theoretical weight: 38.69 KDa
Sequence domains: 5S ribosomal RNA
5.8S ribosomal RNA Chain: h2
Molecule details ›
Chain: h2
Length: 156 nucleotides
Theoretical weight: 50.14 KDa
Sequence domains: 5.8S ribosomal RNA
INTERNAL RIBOSOME ENTRY SITE Chain: E1
Molecule details ›
Chain: E1
Length: 153 nucleotides
Theoretical weight: 48.55 KDa
18S Ribosomal RNA Chain: K3
Molecule details ›
Chain: K3
Length: 1869 nucleotides
Theoretical weight: 602.78 KDa
Sequence domains: Eukaryotic small subunit ribosomal RNA

Ligands and Environments

1 bound ligand:
Ligand ZN 6 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.49Å
Relevant EMDB volumes: EMD-11459

Quick links

Citations

3 review citations

Minding the message: tactics controlling RNA decay, modification, and translation in virus-infected cells.
Burgess et al. (2022)
2 more

1 mention without citation

The Halastavi árva Virus Intergenic Region IRES Promotes Translation by the Simplest Possible Initiation Mechanism.
Abaeva et al. (2020)