6zbp

X-ray diffraction
1.85Å resolution

H11-H4 complex with SARS-CoV-2

Released:
Entry authors: Naismith JH, Huo J, Mikolajek H, Ward P, Dumoux M, Owens RJ, LeBas A

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Spike protein S1 Chain: EEE
Molecule details ›
Chain: EEE
Length: 210 amino acids
Theoretical weight: 23.72 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
  • Canonical: P0DTC2 (Residues: 330-532; Coverage: 16%)
Gene names: 2, S
Sequence domains: Betacoronavirus spike glycoprotein S1, receptor binding
H11-H4 Chain: FFF
Molecule details ›
Chain: FFF
Length: 134 amino acids
Theoretical weight: 15.05 KDa
Source organism: Lama glama
Expression system: Escherichia coli

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P3121
Unit cell:
a: 73.15Å b: 73.15Å c: 131.67Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.187 0.185 0.217
Expression systems:
  • Homo sapiens
  • Escherichia coli