› 6y78

X-ray diffraction
1.7Å resolution

Structure of galectin-3C in complex with lactose determined by serial crystallography using a silicon nitride membrane support

Released:
DOI: 10.2210/pdb6y78/pdb
PDB entry 6y78 coloured by chain, front view.
PDB entry 6y78 coloured by chain, side view.
PDB entry 6y78 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Current status and future opportunities for serial crystallography at MAX IV Laboratory.
Shilova A, Lebrette H, Aurelius O, Nan J, Welin M, Kovacic R, Ghosh S, Safari C, Friel RJ, Milas M, Matej Z, Högbom M, Brändén G, Kloos M, Shoeman RL, Doak B, Ursby T, Håkansson M, Logan DT, Mueller U
J Synchrotron Radiat 27 1095-1102 (2020)
PMID: 32876583

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148215 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Galectin-3 Chain: A
Molecule details ›
Chain: A
Length: 138 amino acids
Theoretical weight: 15.7 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P17931 (Residues: 113-250; Coverage: 55%)
Gene names: LGALS3, MAC2
Sequence domains: Galactoside-binding lectin

Ligands and Environments

Carbohydrate polymer : NEW Components: BGC, GAL
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MAX IV BEAMLINE BioMAX
Spacegroup: P212121
Unit cell:
a: 35.67Å b: 56.36Å c: 61.17Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.167 0.166 0.197
Expression system: Escherichia coli

Quick links

Citations

4 citation in other articles

3D printed devices and infrastructure for liquid sample delivery at the European XFEL.
Vakili et al. (2022)
3 more

1 mention without citation

Current status and future opportunities for serial crystallography at MAX IV Laboratory.
Shilova et al. (2020)