6wax

X-ray diffraction
1.5Å resolution

C-terminal SH2 domain of p120RasGAP

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ras GTPase-activating protein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 107 amino acids
Theoretical weight: 12.47 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P20936 (Residues: 340-444; Coverage: 10%)
Gene names: GAP, RASA, RASA1
Sequence domains: SH2 domain

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P212121
Unit cell:
a: 52.499Å b: 65.588Å c: 71.614Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.18 0.179 0.197
Expression system: Escherichia coli BL21(DE3)