› 6v8o

Electron Microscopy
3.07Å resolution

Function and Biology Details

Reaction catalysed: 
ATP + H(2)O = ADP + phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero 22-mer (preferred)
PDBe Complex ID:
PDB-CPX-150526 (preferred)
Entry contents:
18 distinct polypeptide molecules
Macromolecules (18 distinct):
High temperature lethal protein 1 Chain: C
Molecule details ›
Chain: C
Length: 78 amino acids
Theoretical weight: 9.19 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: Q9URQ5 (Residues: 1-78; Coverage: 100%)
Gene names: DRT1, HTL1, YCR020W-B
Chromatin structure-remodeling complex protein RSC14 Chain: D
Molecule details ›
Chain: D
Length: 180 amino acids
Theoretical weight: 19.83 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P38210 (Residues: 1-180; Coverage: 100%)
Gene names: LDB7, RSC14, YBL006C, YBL0322
Sequence domains: RSC complex, Rsc14/Ldb7 subunit
Chromatin structure-remodeling complex subunit RSC7 Chain: E
Molecule details ›
Chain: E
Length: 435 amino acids
Theoretical weight: 49.72 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P32832 (Residues: 1-435; Coverage: 100%)
Gene names: NPL6, RSC7, YM9582.16C, YMR091C
Sequence domains: Chromatin remodelling complex Rsc7/Swp82 subunit
Chromatin structure-remodeling complex subunit RSC2 Chain: F
Molecule details ›
Chain: F
Length: 889 amino acids
Theoretical weight: 102.44 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: Q06488 (Residues: 1-889; Coverage: 100%)
Gene names: L9638.1, RSC2, YLR357W
Sequence domains:
Chromatin structure-remodeling complex protein RSC3 Chain: G
Molecule details ›
Chain: G
Length: 885 amino acids
Theoretical weight: 101.82 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: Q06639 (Residues: 1-885; Coverage: 100%)
Gene names: D9740.13, RSC3, YDR303C
Sequence domains: Fungal Zn(2)-Cys(6) binuclear cluster domain
Chromatin structure-remodeling complex subunit RSC4 Chain: H
Molecule details ›
Chain: H
Length: 625 amino acids
Theoretical weight: 72.37 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: Q02206 (Residues: 1-625; Coverage: 100%)
Gene names: RSC4, YK107, YKR008W
Sequence domains: Bromodomain
Chromatin structure-remodeling complex protein RSC8 Chains: I, J, K, L
Molecule details ›
Chains: I, J, K, L
Length: 557 amino acids
Theoretical weight: 63.25 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P43609 (Residues: 1-557; Coverage: 100%)
Gene names: RSC8, SWH3, YFR037C
Sequence domains:
Chromatin structure-remodeling complex protein RSC6 Chain: M
Molecule details ›
Chain: M
Length: 483 amino acids
Theoretical weight: 54.22 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P25632 (Residues: 1-483; Coverage: 100%)
Gene names: RSC6, YCR052W, YCR52W
Chromatin structure-remodeling complex subunit RSC9 Chain: N
Molecule details ›
Chain: N
Length: 581 amino acids
Theoretical weight: 65.29 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: Q03124 (Residues: 1-581; Coverage: 100%)
Gene names: RSC9, YM4987.08, YML127W
Chromatin structure-remodeling complex protein RSC58 Chain: O
Molecule details ›
Chain: O
Length: 502 amino acids
Theoretical weight: 57.87 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: Q07979 (Residues: 1-502; Coverage: 100%)
Gene names: RSC58, YLR033W
Sequence domains: Bromodomain
Chromatin structure-remodeling complex subunit SFH1 Chain: Q
Molecule details ›
Chain: Q
Length: 426 amino acids
Theoretical weight: 48.83 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: Q06168 (Residues: 1-426; Coverage: 100%)
Gene names: L8543.4, SFH1, YLR321C
Sequence domains: SNF5 / SMARCB1 / INI1
Nuclear protein STH1/NPS1 Chain: R
Molecule details ›
Chain: R
Length: 1359 amino acids
Theoretical weight: 156.98 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P32597 (Residues: 1-1359; Coverage: 100%)
Gene names: NPS1, STH1, YIL126W
Sequence domains:
Chromatin structure-remodeling complex protein RSC30 Chain: S
Molecule details ›
Chain: S
Length: 883 amino acids
Theoretical weight: 101.45 KDa
Source organism: Saccharomyces cerevisiae S288C
UniProt:
  • Canonical: P38781 (Residues: 1-883; Coverage: 100%)
Gene names: RSC30, YHR056C
Sequence domains: Fungal Zn(2)-Cys(6) binuclear cluster domain
Unknown protein Chain: 2
Molecule details ›
Chain: 2
Length: 28 amino acids
Theoretical weight: 2.4 KDa
Source organism: Saccharomyces cerevisiae S288C
Unknown Protein Chains: 3, 4
Molecule details ›
Chains: 3, 4
Length: 19 amino acids
Theoretical weight: 1.64 KDa
Source organism: Saccharomyces cerevisiae S288C
Unknown protein Chain: 5
Molecule details ›
Chain: 5
Length: 14 amino acids
Theoretical weight: 1.21 KDa
Source organism: Saccharomyces cerevisiae S288C
Unknown Protein Chain: 6
Molecule details ›
Chain: 6
Length: 15 amino acids
Theoretical weight: 1.29 KDa
Source organism: Saccharomyces cerevisiae S288C
Unknown Protein Chain: 7
Molecule details ›
Chain: 7
Length: 49 amino acids
Theoretical weight: 4.19 KDa
Source organism: Saccharomyces cerevisiae S288C

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.07Å
Relevant EMDB volumes: EMD-21107

Quick links

Citations

10 review citations

Structure and Function of Chromatin Remodelers.
Reyes et al. (2021)
9 more

3 mentions without citation

A Structural Model of the Endogenous Human BAF Complex Informs Disease Mechanisms.
Mashtalir et al. (2020)
2 more