X-ray diffraction
2.32Å resolution

Human CLOCK PAS-A domain


Function and Biology Details

Reaction catalysed:
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Circadian locomoter output cycles protein kaput Chain: A
Molecule details ›
Chain: A
Length: 161 amino acids
Theoretical weight: 18.31 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: O15516 (Residues: 105-265; Coverage: 19%)
Gene names: BHLHE8, CLOCK, KIAA0334
Sequence domains: PAS fold

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007 HF
Unit cell:
a: 45.99Å b: 45.36Å c: 75.675Å
α: 90° β: 93.46° γ: 90°
R R work R free
0.183 0.18 0.242
Expression system: Escherichia coli