› 6p8r

X-ray diffraction
2.14Å resolution

Structure of P. aeruginosa ATCC27853 HORMA2

Released:
DOI: 10.2210/pdb6p8r/pdb
PDB entry 6p8r coloured by chain, front view.
PDB entry 6p8r coloured by chain, side view.
PDB entry 6p8r coloured by chain, top view.
Source organism: Pseudomonas aeruginosa
Primary publication:
HORMA Domain Proteins and a Trip13-like ATPase Regulate Bacterial cGAS-like Enzymes to Mediate Bacteriophage Immunity.
Ye Q, Lau RK, Mathews IT, Birkholz EA, Watrous JD, Azimi CS, Pogliano J, Jain M, Corbett KD
Mol Cell 77 709-722.e7 (2020)
PMID: 31932165

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145117 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
CD-NTase-associated protein 7 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 168 amino acids
Theoretical weight: 18.86 KDa
Source organism: Pseudomonas aeruginosa
Expression system: Escherichia coli
UniProt:
  • Canonical: P0DTF6 (Residues: 2-166; Coverage: 99%)
Gene names: A4W92_29530, HORMA2, cap7
Sequence domains: Bacterial HORMA domain 2

Ligands and Environments

1 bound ligand:
Ligand PO4 2 x PO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P41
Unit cell:
a: 106.106Å b: 106.106Å c: 74.789Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.204 0.202 0.233
Expression system: Escherichia coli

Quick links

Citations

19 review citations

Bacterial origins of human cell-autonomous innate immune mechanisms.
Wein et al. (2022)
18 more

1 mention without citation

HORMA Domain Proteins and a Trip13-like ATPase Regulate Bacterial cGAS-like Enzymes to Mediate Bacteriophage Immunity.
Ye et al. (2020)