PDBe 6owm

X-ray diffraction
1.1Å resolution

Horse liver F93W alcohol dehydrogenase complexed with NAD and pentafluorobenzyl alcohol

Released:
Source organism: Equus caballus
Entry author: Plapp BV

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alcohol dehydrogenase E chain Chains: A, B
Molecule details ›
Chains: A, B
Length: 374 amino acids
Theoretical weight: 39.89 KDa
Source organism: Equus caballus
Expression system: Escherichia coli
UniProt:
  • Canonical: P00327 (Residues: 2-375; Coverage: 100%)
Sequence domains:

Ligands and Environments


Cofactor: Ligand NAJ 2 x NAJ
3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-B
Spacegroup: P1
Unit cell:
a: 44.47Å b: 51.44Å c: 92.56Å
α: 92.09° β: 102.95° γ: 110.25°
R-values:
R R work R free
0.124 0.124 0.141
Expression system: Escherichia coli