› 6oqm

X-ray diffraction
2.2Å resolution

crystal structure of the MSH6 PWWP domain

Released:
DOI: 10.2210/pdb6oqm/pdb
PDB entry 6oqm coloured by chain, front view.
PDB entry 6oqm coloured by chain, side view.
PDB entry 6oqm coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Qin S, Tempel W, Bountra C, Arrowsmith CH, Edwards AM, Min J, Structural Genomics Consortium, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156602 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA mismatch repair protein Msh6 Chain: A
Molecule details ›
Chain: A
Length: 130 amino acids
Theoretical weight: 15.15 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P52701 (Residues: 87-198; Coverage: 8%)
Gene names: GTBP, MSH6
Sequence domains: PWWP domain

Ligands and Environments

3 bound ligands:
Ligand UNX 4 x UNX
Ligand MG 1 x MG
Ligand SO4 4 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: R32
Unit cell:
a: 56.421Å b: 56.421Å c: 176.291Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.222 0.217 0.27
Expression system: Escherichia coli BL21(DE3)

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