› 6onb

X-ray diffraction
1.7Å resolution

Crystal Structure of the ZIG-8-RIG-5 IG1-IG1 heterodimer, monoclinic form

Released:
DOI: 10.2210/pdb6onb/pdb
PDB entry 6onb coloured by chain, front view.
PDB entry 6onb coloured by chain, side view.
PDB entry 6onb coloured by chain, top view.
Source organism: Caenorhabditis elegans
Primary publication:
Family of neural wiring receptors in bilaterians defined by phylogenetic, biochemical, and structural evidence.
Cheng S, Park Y, Kurleto JD, Jeon M, Zinn K, Thornton JW, Özkan E
OpenAccess logo Proc Natl Acad Sci U S A 116 9837-9842 (2019)
PMID: 31043568

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-111599 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Zwei Ig domain protein zig-8 Chains: A, C
Molecule details ›
Chains: A, C
Length: 125 amino acids
Theoretical weight: 14.3 KDa
Source organism: Caenorhabditis elegans
Expression system: Trichoplusia ni
UniProt:
  • Canonical: G5ED00 (Residues: 22-137; Coverage: 47%)
Gene names: Y39E4B.8, zig-8
Sequence domains: Immunoglobulin V-set domain
Ig-like domain-containing protein Chains: B, D
Molecule details ›
Chains: B, D
Length: 118 amino acids
Theoretical weight: 13.24 KDa
Source organism: Caenorhabditis elegans
Expression system: Trichoplusia ni
UniProt:
  • Canonical: C6KRM7 (Residues: 81-190; Coverage: 23%)
Gene names: C36F7.4, CELE_C36F7.4, rig-5
Structure domains: Immunoglobulins

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
2 bound ligands:
Ligand SO4 5 x SO4
Ligand NAG 1 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: C2
Unit cell:
a: 87.46Å b: 79.103Å c: 89.977Å
α: 90° β: 94.22° γ: 90°
R-values:
R R work R free
0.176 0.174 0.207
Expression system: Trichoplusia ni

Quick links

Citations

2 review citations

Spatiotemporal Control of Neuronal Remodeling by Cell Adhesion Molecules: Insights From Drosophila.
Meltzer et al. (2022)
1 more

1 mention without citation

Family of neural wiring receptors in bilaterians defined by phylogenetic, biochemical, and structural evidence.
Cheng et al. (2019)