6olf

Electron Microscopy
3.9Å resolution

Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AA and PE tRNAs

Released:
Source organism: Homo sapiens
Related structures: EMD-0599

Function and Biology Details

Reaction catalysed:
The C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero 83-mer (preferred)
Entry contents:
76 distinct polypeptide molecules
7 distinct RNA molecules
Macromolecules (83 distinct):
40S ribosomal protein SA Chain: SA
Molecule details ›
Chain: SA
Length: 221 amino acids
Theoretical weight: 24.77 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P08865 (Residues: 3-223; Coverage: 75%)
Gene names: LAMBR, LAMR1, RPSA
Sequence domains: Ribosomal protein S2
40S ribosomal protein S3a Chain: SB
Molecule details ›
Chain: SB
Length: 214 amino acids
Theoretical weight: 24.89 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P61247 (Residues: 21-234; Coverage: 81%)
Gene names: FTE1, MFTL, RPS3A
40S ribosomal protein S3 Chain: SD
Molecule details ›
Chain: SD
Length: 226 amino acids
Theoretical weight: 25.04 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P23396 (Residues: 2-227; Coverage: 93%)
Gene names: OK/SW-cl.26, RPS3
Sequence domains:
40S ribosomal protein S4, X isoform Chain: SE
Molecule details ›
Chain: SE
Length: 259 amino acids
Theoretical weight: 29.29 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P62701 (Residues: 2-260; Coverage: 99%)
Gene names: CCG2, RPS4, RPS4X, SCAR
Sequence domains:
40S ribosomal protein S5 Chain: SF
Molecule details ›
Chain: SF
Length: 189 amino acids
Theoretical weight: 21.33 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P46782 (Residues: 16-204; Coverage: 93%)
Gene name: RPS5
Sequence domains: Ribosomal protein S7p/S5e
40S ribosomal protein S7 Chain: SH
Molecule details ›
Chain: SH
Length: 189 amino acids
Theoretical weight: 21.6 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P62081 (Residues: 5-193; Coverage: 97%)
Gene name: RPS7
Sequence domains: Ribosomal protein S7e
40S ribosomal protein S8 Chain: SI
Molecule details ›
Chain: SI
Length: 204 amino acids
Theoretical weight: 23.82 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P62241 (Residues: 2-205; Coverage: 98%)
Gene names: OK/SW-cl.83, RPS8
40S ribosomal protein S10 Chain: SK
Molecule details ›
Chain: SK
Length: 98 amino acids
Theoretical weight: 11.77 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P46783 (Residues: 1-98; Coverage: 59%)
Gene name: RPS10
Sequence domains: Plectin/S10 domain
40S ribosomal protein S11 Chain: SL
Molecule details ›
Chain: SL
Length: 153 amino acids
Theoretical weight: 17.79 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P62280 (Residues: 2-154; Coverage: 97%)
Gene name: RPS11
Sequence domains:
40S ribosomal protein S15 Chain: SP
Molecule details ›
Chain: SP
Length: 127 amino acids
Theoretical weight: 14.93 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P62841 (Residues: 10-136; Coverage: 88%)
Gene names: RIG, RPS15
Sequence domains: Ribosomal protein S19
40S ribosomal protein S16 Chain: SQ
Molecule details ›
Chain: SQ
Length: 146 amino acids
Theoretical weight: 16.48 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P62249 (Residues: 1-146; Coverage: 100%)
Gene name: RPS16
Sequence domains: Ribosomal protein S9/S16
40S ribosomal protein S17 Chain: SR
Molecule details ›
Chain: SR
Length: 134 amino acids
Theoretical weight: 15.45 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P08708 (Residues: 2-135; Coverage: 99%)
Gene names: RPS17, RPS17L
40S ribosomal protein S18 Chain: SS
Molecule details ›
Chain: SS
Length: 145 amino acids
Theoretical weight: 17.03 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P62269 (Residues: 1-145; Coverage: 95%)
Gene names: D6S218E, RPS18
Sequence domains: Ribosomal protein S13/S18
40S ribosomal protein S19 Chain: ST
Molecule details ›
Chain: ST
Length: 143 amino acids
Theoretical weight: 15.82 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P39019 (Residues: 2-144; Coverage: 99%)
Gene name: RPS19
Sequence domains: Ribosomal protein S19e
40S ribosomal protein S20 Chain: SU
Molecule details ›
Chain: SU
Length: 104 amino acids
Theoretical weight: 11.77 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P60866 (Residues: 16-119; Coverage: 87%)
Gene name: RPS20
Sequence domains: Ribosomal protein S10p/S20e
40S ribosomal protein S21 Chain: SV
Molecule details ›
Chain: SV
Length: 82 amino acids
Theoretical weight: 8.98 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P63220 (Residues: 1-82; Coverage: 99%)
Gene name: RPS21
Sequence domains: Ribosomal protein S21e
40S ribosomal protein S23 Chain: SX
Molecule details ›
Chain: SX
Length: 141 amino acids
Theoretical weight: 15.63 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P62266 (Residues: 2-142; Coverage: 99%)
Gene name: RPS23
Sequence domains: Ribosomal protein S12/S23
40S ribosomal protein S26 Chain: Sa
Molecule details ›
Chain: Sa
Length: 102 amino acids
Theoretical weight: 11.74 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P62854 (Residues: 2-103; Coverage: 89%)
Gene name: RPS26
40S ribosomal protein S28 Chain: Sc
Molecule details ›
Chain: Sc
Length: 64 amino acids
Theoretical weight: 7.26 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P62857 (Residues: 5-68; Coverage: 93%)
Gene name: RPS28
Sequence domains: Ribosomal protein S28e
40S ribosomal protein S29 Chain: Sd
Molecule details ›
Chain: Sd
Length: 55 amino acids
Theoretical weight: 6.56 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P62273 (Residues: 2-56; Coverage: 98%)
Gene name: RPS29
Sequence domains: Ribosomal protein S14p/S29e
Receptor of activated protein C kinase 1 Chain: Sg
Molecule details ›
Chain: Sg
Length: 312 amino acids
Theoretical weight: 34.57 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P63244 (Residues: 3-314; Coverage: 98%)
Gene names: GNB2L1, HLC7, PIG21, RACK1
Sequence domains: WD domain, G-beta repeat
40S ribosomal protein S2 Chain: SC
Molecule details ›
Chain: SC
Length: 220 amino acids
Theoretical weight: 24.33 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P15880 (Residues: 59-278; Coverage: 75%)
Gene names: RPS2, RPS4
Sequence domains:
40S ribosomal protein S6 Chain: SG
Molecule details ›
Chain: SG
Length: 237 amino acids
Theoretical weight: 27.47 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P62753 (Residues: 1-237; Coverage: 95%)
Gene names: OK/SW-cl.2, RPS6
Sequence domains: Ribosomal protein S6e
40S ribosomal protein S9 Chain: SJ
Molecule details ›
Chain: SJ
Length: 185 amino acids
Theoretical weight: 21.65 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P46781 (Residues: 2-186; Coverage: 95%)
Gene name: RPS9
Sequence domains:
40S ribosomal protein S12 Chain: SM
Molecule details ›
Chain: SM
Length: 118 amino acids
Theoretical weight: 13.22 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P25398 (Residues: 15-132; Coverage: 89%)
Gene name: RPS12
Sequence domains: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
40S ribosomal protein S13 Chain: SN
Molecule details ›
Chain: SN
Length: 150 amino acids
Theoretical weight: 17.13 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P62277 (Residues: 2-151; Coverage: 99%)
Gene name: RPS13
Sequence domains: Ribosomal protein S15
40S ribosomal protein S14 Chain: SO
Molecule details ›
Chain: SO
Length: 137 amino acids
Theoretical weight: 14.66 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P62263 (Residues: 15-151; Coverage: 91%)
Gene names: PRO2640, RPS14
Sequence domains: Ribosomal protein S11
40S ribosomal protein S15a Chain: SW
Molecule details ›
Chain: SW
Length: 129 amino acids
Theoretical weight: 14.73 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P62244 (Residues: 2-130; Coverage: 99%)
Gene names: OK/SW-cl.82, RPS15A
Sequence domains: Ribosomal protein S8
40S ribosomal protein S24 Chain: SY
Molecule details ›
Chain: SY
Length: 131 amino acids
Theoretical weight: 15.2 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P62847 (Residues: 2-132; Coverage: 99%)
Gene name: RPS24
Sequence domains: Ribosomal protein S24e
40S ribosomal protein S25 Chain: SZ
Molecule details ›
Chain: SZ
Length: 73 amino acids
Theoretical weight: 8.25 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P62851 (Residues: 43-115; Coverage: 58%)
Gene name: RPS25
40S ribosomal protein S27 Chain: Sb
Molecule details ›
Chain: Sb
Length: 82 amino acids
Theoretical weight: 9.21 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P42677 (Residues: 2-83; Coverage: 98%)
Gene names: MPS1, RPS27
Sequence domains: Ribosomal protein S27
40S ribosomal protein S30 Chain: Se
Molecule details ›
Chain: Se
Length: 57 amino acids
Theoretical weight: 6.45 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: E9PR30 (Residues: 41-97; Coverage: 58%)
Gene name: FAU
40S ribosomal protein S27a Chain: Sf
Molecule details ›
Chain: Sf
Length: 67 amino acids
Theoretical weight: 7.88 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P62979 (Residues: 85-151; Coverage: 43%)
Gene names: RPS27A, UBA80, UBCEP1
Sequence domains: Ribosomal protein S27a
60S ribosomal protein L8 Chain: A
Molecule details ›
Chain: A
Length: 252 amino acids
Theoretical weight: 27.46 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P62917 (Residues: 2-253; Coverage: 98%)
Gene name: RPL8
Sequence domains:
60S ribosomal protein L3 Chain: B
Molecule details ›
Chain: B
Length: 397 amino acids
Theoretical weight: 45.56 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P39023 (Residues: 2-398; Coverage: 99%)
Gene names: OK/SW-cl.32, RPL3
60S ribosomal protein L4 Chain: C
Molecule details ›
Chain: C
Length: 363 amino acids
Theoretical weight: 41.17 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P36578 (Residues: 3-365; Coverage: 85%)
Gene names: RPL1, RPL4
Sequence domains:
60S ribosomal protein L5 Chain: F
Molecule details ›
Chain: F
Length: 294 amino acids
Theoretical weight: 34.09 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P46777 (Residues: 4-297; Coverage: 99%)
Gene names: MSTP030, RPL5
Sequence domains:
60S ribosomal protein L6 Chain: G
Molecule details ›
Chain: G
Length: 247 amino acids
Theoretical weight: 28.38 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q02878 (Residues: 42-288; Coverage: 86%)
Gene names: RPL6, TXREB1
Sequence domains: Ribosomal protein L6e
60S ribosomal protein L7 Chain: H
Molecule details ›
Chain: H
Length: 225 amino acids
Theoretical weight: 26.59 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P18124 (Residues: 24-248; Coverage: 91%)
Gene name: RPL7
Sequence domains: Ribosomal protein L30p/L7e
60S ribosomal protein L7a Chain: I
Molecule details ›
Chain: I
Length: 234 amino acids
Theoretical weight: 26.72 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P62424 (Residues: 29-262; Coverage: 88%)
Gene names: RPL7A, SURF-3, SURF3
Sequence domains: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
60S ribosomal protein L9 Chain: J
Molecule details ›
Chain: J
Length: 191 amino acids
Theoretical weight: 21.77 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P32969 (Residues: 1-191; Coverage: 100%)
Gene names: OK/SW-cl.103, RPL9, RPL9P7, RPL9P8, RPL9P9
Sequence domains: Ribosomal protein L6
60S ribosomal protein L10 Chain: K
Molecule details ›
Chain: K
Length: 211 amino acids
Theoretical weight: 24.38 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P27635 (Residues: 3-213; Coverage: 99%)
Gene names: DXS648E, QM, RPL10
Sequence domains: Ribosomal protein L16p/L10e
60S ribosomal protein L11 Chain: L
Molecule details ›
Chain: L
Length: 169 amino acids
Theoretical weight: 19.27 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P62913 (Residues: 9-177; Coverage: 95%)
Gene name: RPL11
Sequence domains:
60S ribosomal protein L13 Chain: M
Molecule details ›
Chain: M
Length: 205 amino acids
Theoretical weight: 23.57 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P26373 (Residues: 2-206; Coverage: 97%)
Gene names: BBC1, OK/SW-cl.46, RPL13
Sequence domains: Ribosomal protein L13e
60S ribosomal protein L14 Chain: N
Molecule details ›
Chain: N
Length: 139 amino acids
Theoretical weight: 16.22 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P50914 (Residues: 2-140; Coverage: 65%)
Gene name: RPL14
Sequence domains: Ribosomal protein L14
60S ribosomal protein L15 Chain: O
Molecule details ›
Chain: O
Length: 203 amino acids
Theoretical weight: 24.08 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P61313 (Residues: 2-204; Coverage: 100%)
Gene names: EC45, RPL15, TCBAP0781
Sequence domains: Ribosomal L15
60S ribosomal protein L13a Chain: P
Molecule details ›
Chain: P
Length: 195 amino acids
Theoretical weight: 22.82 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P40429 (Residues: 5-199; Coverage: 96%)
Gene name: RPL13A
Sequence domains: Ribosomal protein L13
60S ribosomal protein L17 Chain: Q
Molecule details ›
Chain: Q
Length: 153 amino acids
Theoretical weight: 17.76 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P18621 (Residues: 2-154; Coverage: 83%)
Gene name: RPL17
Sequence domains: Ribosomal protein L22p/L17e
60S ribosomal protein L18 Chain: R
Molecule details ›
Chain: R
Length: 187 amino acids
Theoretical weight: 21.56 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q07020 (Residues: 2-188; Coverage: 100%)
Gene name: RPL18
Sequence domains: Ribosomal protein 60S L18 and 50S L18e
60S ribosomal protein L19 Chain: S
Molecule details ›
Chain: S
Length: 181 amino acids
Theoretical weight: 21.74 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P84098 (Residues: 2-182; Coverage: 92%)
Gene name: RPL19
Sequence domains: Ribosomal protein L19e
60S ribosomal protein L18a Chain: T
Molecule details ›
Chain: T
Length: 175 amino acids
Theoretical weight: 20.66 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q02543 (Residues: 1-175; Coverage: 99%)
Gene name: RPL18A
Sequence domains: Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A
60S ribosomal protein L21 Chain: U
Molecule details ›
Chain: U
Length: 157 amino acids
Theoretical weight: 18.28 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P46778 (Residues: 2-158; Coverage: 98%)
Gene name: RPL21
60S ribosomal protein L22 Chain: V
Molecule details ›
Chain: V
Length: 99 amino acids
Theoretical weight: 11.48 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P35268 (Residues: 18-116; Coverage: 77%)
Gene name: RPL22
Similar to ribosomal protein L23 Chain: W
Molecule details ›
Chain: W
Length: 129 amino acids
Theoretical weight: 13.83 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9BTQ7 (Residues: 6-134; Coverage: 96%)
Sequence domains: Ribosomal protein L14p/L23e
60S ribosomal protein L24 Chain: X
Molecule details ›
Chain: X
Length: 121 amino acids
Theoretical weight: 14.09 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P83731 (Residues: 2-122; Coverage: 77%)
Gene name: RPL24
60S ribosomal protein L23a Chain: Y
Molecule details ›
Chain: Y
Length: 117 amino acids
Theoretical weight: 13.61 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P62750 (Residues: 39-155; Coverage: 75%)
Gene name: RPL23A
Sequence domains: Ribosomal protein L23
60S ribosomal protein L26 Chain: Z
Molecule details ›
Chain: Z
Length: 134 amino acids
Theoretical weight: 15.89 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P61254 (Residues: 1-134; Coverage: 92%)
Gene name: RPL26
Sequence domains:
60S ribosomal protein L27a Chain: b
Molecule details ›
Chain: b
Length: 147 amino acids
Theoretical weight: 16.47 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P46776 (Residues: 2-148; Coverage: 99%)
Gene name: RPL27A
Sequence domains: Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
60S ribosomal protein L29 Chain: c
Molecule details ›
Chain: c
Length: 121 amino acids
Theoretical weight: 13.97 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P47914 (Residues: 2-122; Coverage: 76%)
Gene name: RPL29
Sequence domains: Ribosomal L29e protein family
60S ribosomal protein L30 Chain: d
Molecule details ›
Chain: d
Length: 103 amino acids
Theoretical weight: 11.5 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P62888 (Residues: 7-109; Coverage: 90%)
Gene name: RPL30
Sequence domains: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
60S ribosomal protein L31 Chain: e
Molecule details ›
Chain: e
Length: 106 amino acids
Theoretical weight: 12.51 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P62899 (Residues: 18-123; Coverage: 85%)
Gene name: RPL31
Sequence domains: Ribosomal protein L31e
60S ribosomal protein L32 Chain: f
Molecule details ›
Chain: f
Length: 129 amino acids
Theoretical weight: 15.18 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P62910 (Residues: 2-130; Coverage: 96%)
Gene names: PP9932, RPL32
Sequence domains: Ribosomal protein L32
60S ribosomal protein L35a Chain: g
Molecule details ›
Chain: g
Length: 109 amino acids
Theoretical weight: 12.43 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P18077 (Residues: 2-110; Coverage: 99%)
Gene names: GIG33, RPL35A
Sequence domains: Ribosomal protein L35Ae
60S ribosomal protein L34 Chain: h
Molecule details ›
Chain: h
Length: 114 amino acids
Theoretical weight: 12.99 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P49207 (Residues: 2-115; Coverage: 97%)
Gene name: RPL34
60S ribosomal protein L35 Chain: i
Molecule details ›
Chain: i
Length: 122 amino acids
Theoretical weight: 14.46 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P42766 (Residues: 2-123; Coverage: 99%)
Gene name: RPL35
Sequence domains: Ribosomal L29 protein
60S ribosomal protein L36 Chain: j
Molecule details ›
Chain: j
Length: 97 amino acids
Theoretical weight: 11.37 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: Q9Y3U8 (Residues: 5-101; Coverage: 92%)
Gene name: RPL36
60S ribosomal protein L37 Chain: k
Molecule details ›
Chain: k
Length: 84 amino acids
Theoretical weight: 9.86 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P61927 (Residues: 2-85; Coverage: 87%)
Gene name: RPL37
Sequence domains: Ribosomal protein L37e
60S ribosomal protein L38 Chain: l
Molecule details ›
Chain: l
Length: 69 amino acids
Theoretical weight: 8.11 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P63173 (Residues: 2-70; Coverage: 99%)
Gene name: RPL38
Sequence domains: Ribosomal L38e protein family
60S ribosomal protein L39 Chain: m
Molecule details ›
Chain: m
Length: 50 amino acids
Theoretical weight: 6.3 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P62891 (Residues: 2-51; Coverage: 98%)
Gene name: RPL39
Sequence domains: Ribosomal L39 protein
60S ribosomal protein L40 Chain: n
Molecule details ›
Chain: n
Length: 50 amino acids
Theoretical weight: 5.96 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P62987 (Residues: 78-127; Coverage: 39%)
Gene names: UBA52, UBCEP2
Sequence domains: Ribosomal L40e family
60S ribosomal protein L41 Chain: o
Molecule details ›
Chain: o
Length: 25 amino acids
Theoretical weight: 3.47 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P62945 (Residues: 1-25; Coverage: 100%)
Gene name: RPL41
Sequence domains: Ribosomal protein L41
60S ribosomal protein L36a Chain: p
Molecule details ›
Chain: p
Length: 105 amino acids
Theoretical weight: 12.35 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P83881 (Residues: 2-106; Coverage: 99%)
Gene names: GIG15, MIG6, RPL36A, RPL44
Sequence domains: Ribosomal protein L44
60S ribosomal protein L37a Chain: q
Molecule details ›
Chain: q
Length: 91 amino acids
Theoretical weight: 10.17 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P61513 (Residues: 2-92; Coverage: 99%)
Gene name: RPL37A
Sequence domains: Ribosomal L37ae protein family
60S ribosomal protein L28 Chain: r
Molecule details ›
Chain: r
Length: 122 amino acids
Theoretical weight: 13.99 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P46779 (Residues: 2-123; Coverage: 89%)
Gene name: RPL28
Sequence domains: Ribosomal L28e protein family
E-Cad/CTF1 Chain: y
Molecule details ›
Chain: y
Length: 39 amino acids
Theoretical weight: 4.01 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P12830 (Residues: 693-697, 698-730; Coverage: 4%)
Gene names: CDH1, CDHE, UVO
60S ribosomal protein L27 Chain: a
Molecule details ›
Chain: a
Length: 134 amino acids
Theoretical weight: 15.65 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P61353 (Residues: 3-136; Coverage: 99%)
Gene name: RPL27
Sequence domains:
18S Ribosomal RNA Chain: S2
Molecule details ›
Chain: S2
Length: 1714 nucleotides
Theoretical weight: 553.51 KDa
5.8S ribosomal RNA Chain: D
Molecule details ›
Chain: D
Length: 157 nucleotides
Theoretical weight: 50.45 KDa
5S ribosomal RNA Chain: E
Molecule details ›
Chain: E
Length: 119 nucleotides
Theoretical weight: 38.39 KDa
28S ribosomal RNA Chain: t
Molecule details ›
Chain: t
Length: 3607 nucleotides
Theoretical weight: 1168.72 KDa
AA tRNA Chain: v
Molecule details ›
Chain: v
Length: 76 nucleotides
Theoretical weight: 24.44 KDa
Messenger RNA Chain: w
Molecule details ›
Chain: w
Length: 10 nucleotides
Theoretical weight: 3.19 KDa
PE tRNA Chain: u
Molecule details ›
Chain: u
Length: 76 nucleotides
Theoretical weight: 24.41 KDa

Ligands and Environments

Experiments and Validation Details

Entry percentile scores
Resolution: 3.9Å
Relevant EMDB volumes: EMD-0599