PDBe 6n8c

Solution NMR

Structure of the Huntingtin tetramer/dimer mixture determined by paramagnetic NMR

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Huntingtin Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 23 amino acids
Theoretical weight: 2.74 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P42858 (Residues: 2-24; Coverage: 1%)
Gene names: HD, HTT, IT15

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 3%
Refinement method: simulated annealing
Chemical shifts: BMR30545  
Expression system: Escherichia coli