6n35

X-ray diffraction
1.75Å resolution

Anti-HIV-1 Fab 2G12 + Man1-2 re-refinement

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Fab 2G12 light chain Chains: K, L
Molecule details ›
Chains: K, L
Length: 213 amino acids
Theoretical weight: 23.25 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
Fab 2G12 heavy chain Chains: H, M
Molecule details ›
Chains: H, M
Length: 224 amino acids
Theoretical weight: 23.85 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL11-1
Spacegroup: P212121
Unit cell:
a: 81.725Å b: 94.034Å c: 169.187Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.208 0.206 0.238
Expression system: Cricetulus griseus