› 6m7e

X-ray diffraction
2.42Å resolution

Structure of bovine lactoperoxidase with multiple iodide ions in the distaline heme cavity.

Released:
DOI: 10.2210/pdb6m7e/pdb
PDB entry 6m7e coloured by chain, front view.
PDB entry 6m7e coloured by chain, side view.
PDB entry 6m7e coloured by chain, top view.
Source organism: Bos taurus
Entry authors: Maurya A, Viswanathan V, Pandey N, Singh AK, Sinha M, Kaur P, Sharma S, Singh TP

Function and Biology Details

Reaction catalysed: 
2 phenolic donor + H(2)O(2) = 2 phenoxyl radical of the donor + 2 H(2)O
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160329 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Lactoperoxidase Chain: A
Molecule details ›
Chain: A
Length: 595 amino acids
Theoretical weight: 67.77 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P80025 (Residues: 118-712; Coverage: 86%)
Gene name: LPO
Sequence domains: Animal haem peroxidase

Ligands and Environments


Cofactor: Ligand HEM 1 x HEM
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
7 bound ligands:
Ligand CA 1 x CA
Ligand NAG 3 x NAG
Ligand IOD 16 x IOD
Ligand SCN 4 x SCN
Ligand GOL 1 x GOL
Ligand OSM 1 x OSM
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: P21
Unit cell:
a: 53.81Å b: 80.673Å c: 74.442Å
α: 90° β: 103.07° γ: 90°
R-values:
R R work R free
0.188 0.184 0.269

Quick links