› 6jli

X-ray diffraction
1.78Å resolution

Crystal structure of CTLD7 domain of human PLA2R

Released:
DOI: 10.2210/pdb6jli/pdb
PDB entry 6jli coloured by chain, front view.
PDB entry 6jli coloured by chain, side view.
PDB entry 6jli coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of the CTLD7 domain of human M-type phospholipase A2 receptor.
Yu B, Hu Z, Kong D, Cheng C, He Y
J Struct Biol 207 295-300 (2019)
PMID: 31271865

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171505 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Soluble secretory phospholipase A2 receptor Chain: A
Molecule details ›
Chain: A
Length: 133 amino acids
Theoretical weight: 15.32 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q13018 (Residues: 1108-1234; Coverage: 9%)
Gene names: CLEC13C, PLA2R1
Sequence domains: Lectin C-type domain

Ligands and Environments

1 bound ligand:
Ligand NAG 1 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL18U1
Spacegroup: P3221
Unit cell:
a: 70.652Å b: 70.652Å c: 64.641Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.164 0.162 0.187
Expression system: Trichoplusia ni

Quick links

Citations

2 citation in other articles

Refining Our Understanding of the PLA2R-Antibody Response in Primary Membranous Nephropathy: Looking Forward, Looking Back.
Beck et al. (2020)
1 more

3 mentions without citation

Secreted Phospholipases A2 - not just Enzymes: Revisited.
IvanuĊĦec et al. (2022)
2 more