6irt

Electron Microscopy
3.5Å resolution

human LAT1-4F2hc complex bound with BCH

Released:
Source organism: Homo sapiens
Related structures: EMD-9722

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Aamy domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 647 amino acids
Theoretical weight: 70.16 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: J3KPF3 (Residues: 2-631; Coverage: 100%)
Gene names: SLC3A2, hCG_2016598
Sequence domains:
Large neutral amino acids transporter small subunit 1 Chain: B
Molecule details ›
Chain: B
Length: 527 amino acids
Theoretical weight: 57.24 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q01650 (Residues: 2-507; Coverage: 100%)
Gene names: CD98LC, LAT1, MPE16, SLC7A5
Sequence domains: Amino acid permease

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.5Å
Relevant EMDB volumes: EMD-9722
Expression system: Homo sapiens