› 6ip9

X-ray diffraction
1.85Å resolution

Crystal Structure of Lanthanum ion (La3+) bound bovine alpha-lactalbumin

Released:
DOI: 10.2210/pdb6ip9/pdb
PDB 6ip9 coloured by chain and viewed from the front.
PDB 6ip9 coloured by chain and viewed from the side.
PDB 6ip9 coloured by chain and viewed from the top.
Source organism: Bos taurus
Primary publication:
Cytotoxicity of apo bovine α-lactalbumin complexed with La3+ on cancer cells supported by its high resolution crystal structure.
Yarramala DS, Prakash P, Ranade DS, Doshi S, Kulkarni PP, Bhaumik P, Rao CP
OpenAccess logo Sci Rep 9 1780 (2019)
PMID: 30741951

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alpha-lactalbumin Chain: A
Molecule details ›
Chain: A
Length: 123 amino acids
Theoretical weight: 14.2 KDa
Source organism: Bos taurus
Expression system: Enterobacteria phage L1
UniProt:
  • Canonical: P00711 (Residues: 20-142; Coverage: 100%)
Gene names: ALACTA, LALBA
Sequence domains: C-type lysozyme/alpha-lactalbumin family
Structure domains: Lysozyme

Ligands and Environments

3 bound ligands:
Ligand SO4 1 x SO4
Ligand GOL 1 x GOL
Ligand LA 1 x LA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007 HF
Spacegroup: P3121
Unit cell:
a: 47.45Å b: 47.45Å c: 89.84Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.198 0.197 0.216
Expression system: Enterobacteria phage L1

Quick links

Citations

1 review citation

α-Lactalbumin, Amazing Calcium-Binding Protein.
Permyakov EA. (2020)