PDBe 6hon

X-ray diffraction
2.2Å resolution

Drosophila NOT4 CBM peptide bound to human CAF40

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
CCR4-NOT transcription complex subunit 9 Chains: A, C
Molecule details ›
Chains: A, C
Length: 273 amino acids
Theoretical weight: 31.07 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q92600 (Residues: 19-285; Coverage: 89%)
Gene names: CNOT9, RCD1, RQCD1
Sequence domains: Cell differentiation family, Rcd1-like
CCR4-NOT transcription complex subunit 4, isoform L Chains: B, D
Molecule details ›
Chains: B, D
Length: 26 amino acids
Theoretical weight: 2.94 KDa
Source organism: Drosophila melanogaster
Expression system: Not provided
UniProt:
  • Canonical: M9PCL9 (Residues: 813-838; Coverage: 3%)
Gene names: CG31716, CG5244, CG5251, Cnot4, Cont4, Dmel\CG31716, Dmel_CG31716, NOT4, Not4, Q8IPB9_DROME, cg5251, not4

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: I212121
Unit cell:
a: 85.63Å b: 90.32Å c: 196.99Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.195 0.193 0.23
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided