6h78

X-ray diffraction
2.7Å resolution

E1 enzyme for ubiquitin like protein activation.

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ubiquitin-like modifier-activating enzyme 5 Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P
Length: 300 amino acids
Theoretical weight: 33.28 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9GZZ9 (Residues: 36-335; Coverage: 74%)
Gene names: UBA5, UBE1DC1
Sequence domains: ThiF family

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE MASSIF-1
Spacegroup: P21
Unit cell:
a: 143.86Å b: 151.933Å c: 153.543Å
α: 90° β: 93.07° γ: 90°
R-values:
R R work R free
0.19 0.19 0.242
Expression system: Escherichia coli