6h5i

Electron Microscopy
3.9Å resolution

Single Particle Cryo-EM map of human Transferrin receptor 1 - H-Ferritin complex.

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero 26-mer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ferritin heavy chain Chains: Aa, Ac, Ad, Ae, Af, Ag, Ah, Ai, Aj, Ak, Al, Am, An, Ao, Ap, Ar, As, At, Au, Av, Aw, Ax, Ay, Az
Molecule details ›
Chains: Aa, Ac, Ad, Ae, Af, Ag, Ah, Ai, Aj, Ak, Al, Am, An, Ao, Ap, Ar, As, At, Au, Av, Aw, Ax, Ay, Az
Length: 172 amino acids
Theoretical weight: 20.12 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P02794 (Residues: 6-177; Coverage: 94%)
Gene names: FTH, FTH1, FTHL6, OK/SW-cl.84, PIG15
Sequence domains: Ferritin-like domain
Transferrin receptor protein 1, serum form Chains: Ab, Aq
Molecule details ›
Chains: Ab, Aq
Length: 640 amino acids
Theoretical weight: 71.81 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P02786 (Residues: 121-760; Coverage: 84%)
Gene name: TFRC
Sequence domains:

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.9Å
Relevant EMDB volumes: EMD-0140
Expression systems:
  • Escherichia coli
  • Homo sapiens